Evidence map›Paper›PMID 42305823›Full record

ArticleJTCVS structural and endovascular2024

Long-term durability of bioprosthetic aortic valve replacement in young patients with bicuspid aortic stenosis.

Christopher K Mehta, Tom X Liu, Abigail S Baldridge, Jane Kruse, Jyothy Puthumana, Robert O Bonow, Duc T Pham, Douglas R Johnston, S Christopher Malaisrie, Patrick M McCarthy

Abstract read
In one paragraph

Article in JTCVS structural and endovascular, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christopher K MehtaDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
Tom X LiuDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
Abigail S BaldridgeDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
Jane KruseDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
Jyothy PuthumanaDivision of Cardiology, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
Robert O BonowDivision of Cardiology, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
Duc T PhamDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
Douglas R JohnstonDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
S Christopher MalaisrieDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.
Patrick M McCarthyDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, Ill.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine long-term surgical aortic valve replacement (SAVR) outcomes for young (ie, younger than age 65 years) patients with bicuspid aortic valve and aortic stenosis (AS) with or without concomitant aneurysm. Background: There are few studies evaluating the early and late outcomes of SAVR in young patients (younger than age 65 years) with bicuspid aortic valve and AS. Methods: Using institutional data from 2004 through 2022, 498 patients with bicuspid aortic valve younger than age 65 years underwent SAVR for AS with bioprosthetic valves. We examined operative outcomes, long-term valve durability, and reintervention. Results: The total cohort comprised 281 patients undergoing isolated SAVR and 217 with concomitant aneurysm repair (SAVR/aneurysm). The average age was 55 ± 8 years, with Society of Thoracic Surgeons predicted risk of mortality score of median 0.7 (IQR 0.5, 1.0) and mean valve size of 25 mm. Operative mortality (0.7% vs 1.4%; Conclusions: Bicuspid AS is common in patients younger than 65 years and management includes consideration of future valve intervention. SAVR confers excellent operative and reoperative outcomes, 10-year durability, and valve function. These results may support initial SAVR when considering lifetime management of AS.

Indexed as

aortic stenosisaortic valve replacementbicuspid aortic valvelifetime management

Identifiers

PMID42305823
PMCPMC13244742

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.