Evidence map›Paper›PMID 42305733›Full record

ArticleIJTLD open2026

Scoping review of community-wide screening to break the chain of TB transmission.

C R Horsburgh, H E Jenkins, E A Kendall, H Esmail, C-Y Chiang, L F White, G B Marks

Abstract read
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Article in IJTLD open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C R HorsburghDepartments of Global Health, Epidemiology and Medicine, Boston University Schools of Public Health and Medicine, Boston, MA, USA.
H E JenkinsDepartment of Biostatistics, Boston University Schools of Public Health, Boston, MA, USA.
E A KendallDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
H EsmailMRC Clinical Trials Unit at University College London and WHO Collaborating Centre for TB Research and Innovation, UCL Centre for Global TB Research, Institute for Global Health, University College London, London, UK.
C-Y ChiangDivision of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, and Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
L F WhiteDepartment of Biostatistics, Boston University Schools of Public Health, Boston, MA, USA.
G B MarksBurnet Institute, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundActive screening for TB may help address the global TB burden, but the optimal screening strategies are not defined. We have reviewed the effectiveness of community-wide active screening programmes to assess the characteristics associated with a reduction in TB.

methodsWe performed a scoping review of community-wide screening studies since 1945 and summarised those that either provided TB prevalence data at the start and end of screening or compared the screening programme to a control community where screening was not performed.

resultsEight studies were identified in China, Czechoslovakia, Kenya, Malawi, South Africa, Uganda, Vietnam, Zambia, and Zimbabwe. Initial TB prevalence ranged from 84/100,000 to 1,014/100,000. Five studies demonstrated TB prevalence reductions from 44% to >80%, one showed evidence both for and against reduction, and two failed to demonstrate reduction. The successful studies were those that found, over the duration of the multi-year intervention, between 124% and 252% of the number of people with TB estimated to have been in the population at the beginning of the intervention, while unsuccessful studies found only 69%-83%.

conclusionReducing the force of infection can be accomplished by performing multiple cycles of community-wide screening to reach substantial numbers of community members with TB.

Indexed as

asymptomatic TBTB prevalencetuberculosis

Identifiers

PMID42305733
PMCPMC13268051

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