ArticleIJTLD open2026
Defining person-centred treatment support for multidrug-resistant TB: a discrete choice experiment.
Article in IJTLD open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
backgroundMultidrug-resistant TB (MDR-TB) treatment remains challenging, with significant toxicity and associated hardships that undermine adherence and cure rates. Support packages may improve outcomes, but the features most valued by people with MDR-TB are unknown.
methodsA discrete choice experiment was performed among adults receiving MDR-TB treatment in Lusaka, Zambia. Five features (3-4 levels each) comprising a support package were evaluated through 12 choice tasks comparing hypothetical packages.
resultsAmong 99 participants (median age 36 years, 68.9% men, 42.4% HIV-positive), material support was the most valued feature (relative importance [RI] = 45.7%), with transport vouchers plus food assistance being the most preferred option. Visit frequency was also important (RI = 26.7%), with similar preferences for monthly and bimonthly visits. Participants preferred phone calls for visit reminders (RI = 11.8%), health care workers for emotional support (RI = 11.2%), and community-based health care workers or loved ones for treatment observation (RI = 4.7%). Three distinct preference groups were identified - all highly valued material support but varied in their preferences for other support features and their delivery.
conclusionAmong people with MDR-TB in Zambia, material support mechanisms and less frequent clinic visits were highly valued. Incorporating patient preferences into treatment programmes could optimise MDR-TB care and improve treatment adherence and outcomes.
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