Evidence map›Paper›PMID 42305620›Full record

ArticleiScience2026

LRP1 activated by AT2 cell-secreted MDK inhibits fibrotic ferroptosis in idiopathic pulmonary fibrosis.

Wenjie Hua, Zitao Wang, Zhenhang Dai, Zhenyu Zhang, Xiaoshan Li, Bo Wu, Man Huang, Jingyu Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenjie HuaWuxi School of Medicine, Jiangnan University, NO.1800, Lihu Avenue, Wuxi 214122, China.
Zitao WangLung Transplantation Department, Second Affiliated Hospital of Zhejiang University, NO.1511, Jianghong Road, Hangzhou 310052, China.
Zhenhang DaiLung Transplantation Department, Second Affiliated Hospital of Zhejiang University, NO.1511, Jianghong Road, Hangzhou 310052, China.
Zhenyu ZhangLung Transplantation Department, The Affiliated Wuxi People's Hospital of Nanjing Medical University, NO 299, Qingyang Road, Wuxi 214023, China.
Xiaoshan LiLung Transplantation Department, The Affiliated Wuxi People's Hospital of Nanjing Medical University, NO 299, Qingyang Road, Wuxi 214023, China.
Bo WuLung Transplantation Department, The Affiliated Wuxi People's Hospital of Nanjing Medical University, NO 299, Qingyang Road, Wuxi 214023, China.
Man HuangGeneral Intensive Care Unit, Second Affiliated Hospital of Zhejiang University, NO.1511, Jianghong Road, Hangzhou 310052, China.
Jingyu ChenWuxi School of Medicine, Jiangnan University, NO.1800, Lihu Avenue, Wuxi 214122, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is characterized by alveolar injury and pathological fibroblast expansion. Our study investigated the aberrant intercellular communication underlying this process. By analyzing single-cell sequencing from GEO database and experimentally validating the results

Indexed as

biological sciencescell biologymolecular biology

Identifiers

PMID42305620
PMCPMC13265906

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.