Evidence map›Paper›PMID 42305609›Full record

ArticleiScience2026

Systematic infectome-phenome profiling reveals cryptococcal infection-associated proteins driving immune system remodeling and immunization potential.

Brianna Ball, Norris Chan, Hannah West, Arjun Sukumaran, Duncan Carruthers-Lay, Michael Woods, Mayara Silva, Austin Pozniak, Priyanka Pundir, Jennifer Geddes-McAlister

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Brianna BallDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Norris ChanDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Hannah WestDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Arjun SukumaranDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Duncan Carruthers-LayDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Michael WoodsDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Mayara SilvaDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Austin PozniakDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Priyanka PundirDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Jennifer Geddes-McAlisterDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal infections are an escalating global health challenge driven by host immune status and antifungal resistance. Here, we present an integrated infectome-phenome platform that combines high-resolution proteomics with systematic phenotypic profiling to map host-pathogen interactions in

Indexed as

immunologyproteomics

Identifiers

PMID42305609
PMCPMC13267614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.