Evidence map›Paper›PMID 42305603›Full record

ArticleiScience2026

Brain and central nervous system cancer burden in children across Asia.

Weiqin Zhang, Wenwen Lv, Rui Chen, Taixiang Liu

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Weiqin ZhangDepartment of Neurology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou 310052, China.
Wenwen LvInstitute of Clinical Medicine Shanghai Jiaotong University School of Medicine, Shanghai, China.
Rui ChenDepartment of Neonatal Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou 310052, China.
Taixiang LiuDepartment of Neonatal intensive care unit, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou 310052, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain and central nervous system cancers are a major cause of cancer-related morbidity and mortality in children. However, evidence on long-term trends and inequalities across Asia remains limited. Using Global Burden of Disease 2023 data, we analyzed the burden among children aged 0-14 years in Asia from 1990 to 2023 and projected trends to 2050. Age-standardized incidence, mortality, and disability-adjusted life year (DALY) rates were lower in 2023 than in 1990, but no significant regional trends were observed. Substantial geographical heterogeneity persisted, with higher burdens in Central and Western Asia. Infants bore the highest burden, and boys had higher incidence and mortality than girls. Inequality analyses indicated persistent concentration of burden in lower-socio-demographic index settings. Projections suggested a continued decline in overall burden to 2050 but with considerable uncertainty. These findings highlight persistent regional and socio-economic disparities and require strengthened early diagnosis, treatment access, and survivorship care in resource-limited settings.

Indexed as

health sciencesinternal medicinemedical specialtymedicineoncologypublic health

Identifiers

PMID42305603
PMCPMC13266199

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.