Evidence map›Paper›PMID 42305477›Full record

ArticleTranslational cancer research2026

Integrative single-cell and bulk transcriptomics identify an

Aiguo Zhu, Yuren Xia, Xin Li, Zhengchao Jin, Jian Wang, Yi Pan

Abstract read
In one paragraph

Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aiguo Zhu *Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Yuren Xia *Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Xin Li *Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Zhengchao JinTianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Jian WangTianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Yi PanTianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Activating anaplastic lymphoma kinase ( Methods: We integrated a public single-cell atlas of high-risk NB from CELL×GENE with bulk RNA sequencing (RNA-seq) cohorts and NB cell-line datasets. Differential expression between Results: Three concordant Conclusions: Cross-context transcriptomic integration identified a minimal

Indexed as

anaplastic lymphoma kinase mutation (ALK mutation)bulk RNA sequencing integration (bulk RNA-seq integration)Neuroblastoma (NB)prognostic signaturesingle-cell RNA sequencing (scRNA-seq)

Identifiers

PMID42305477
PMCPMC13265170

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.