Evidence map›Paper›PMID 42305411›Full record

ArticleProceedings of machine learning research2026

Classifying Phonotrauma Severity from Vocal Fold Images with Soft Ordinal Regression.

Katie Matton, Purvaja Balaji, Hamzeh Ghasemzadeh, Jameson C Cooper, Daryush D Mehta, Jarrad H Van Stan, Robert E Hillman, Rosalind Picard, John Guttag, S Mazdak Abulnaga

Abstract read
In one paragraph

Article in Proceedings of machine learning research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katie MattonMassachusetts Institute of Technology.
Purvaja BalajiMassachusetts Institute of Technology.
Hamzeh GhasemzadehSchool of Communication Sciences and Disorders, University of Central Florida.
Jameson C CooperCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital; Department of Surgery, Harvard Medical School; Massachusetts General Hospital Institute of Health Professions.
Daryush D MehtaCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital; Department of Surgery, Harvard Medical School; Massachusetts General Hospital Institute of Health Professions.
Jarrad H Van StanCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital; Department of Surgery, Harvard Medical School; Massachusetts General Hospital Institute of Health Professions.
Robert E HillmanCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital; Department of Surgery, Harvard Medical School; Massachusetts General Hospital Institute of Health Professions.
Rosalind PicardMassachusetts Institute of Technology.
John GuttagMassachusetts Institute of Technology.
S Mazdak AbulnagaAthinoula Martinos Center, Massachusetts General Hospital, Harvard Medical School; Massachusetts Institute of Technology.

Funding

Functionally guided adult whole brain cell atlas in human and NHPUM1MH130981 · NIMH · ALLEN INSTITUTE · PI Ed Lein, Hongkui Zeng · 2022 to 2026
$91.9M
Use of ambulatory biofeedback to improve behavioral treatment of vocal hyperfunctionP50DC015446 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI Robert E Hillman · 2017 to 2026
$25.5M
Nobrainer: A robust and validated neural network tool suite for imagersRF1MH121885 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GHOSH, SATRAJIT SUJIT · 2020 to 2020
$2.4M
Ambulatory monitoring of vocal function to improve voice disorder assessmentR33DC011588 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI HILLMAN, ROBERT E · 2012 to 2015
$2.3M
Open-source software for multi-scale mapping of the human brainRF1MH123195 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE, IGLESIAS GONZALEZ, JUAN EUGENIO · 2020 to 2020
$2.0M
NIDCD NIH HHS P50 DC015446NIDCD NIH HHS R33 DC011588NIMH NIH HHS RF1 MH121885NIMH NIH HHS RF1 MH123195NIMH NIH HHS UM1 MH130981
6 · The paper itself

Abstract

Phonotrauma refers to vocal fold tissue damage resulting from exposure to forces during voicing. It occurs on a continuum from mild to severe, and treatment options can vary based on severity. Assessment of severity involves a clinician's expert judgment, which is costly and can vary widely in reliability. In this work, we present the first method for automatically classifying phonotrauma severity from vocal fold images. To account for the ordinal nature of the labels, we adopt a widely used ordinal regression framework. To account for label uncertainty, we propose a novel modification to ordinal regression loss functions that enables them to operate on soft labels reflecting annotator rating distributions. Our proposed soft ordinal regression method achieves predictive performance approaching that of clinical experts, while producing well-calibrated uncertainty estimates. By providing an automated tool for phonotrauma severity assessment, our work can enable large-scale studies of phonotrauma, ultimately leading to improved clinical understanding and patient care.

Indexed as

ordinal regressionphonotraumasoft label learningvocal folds

Identifiers

PMID42305411
PMCPMC13268597

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.