Evidence map›Paper›PMID 42305377›Full record

ArticleJTCVS structural and endovascular2024

Left atrial appendage exclusion during open cardiac surgery in patients without atrial fibrillation reduces 4-year ischemic stroke and mortality.

Patrick M McCarthy, Roxana Mehran, Marc Gerdisch, Basel Ramlawi, Randall J Lee, Michael A Ferguson, Jane Kruse, Richard P Whitlock

Abstract read
In one paragraph

Article in JTCVS structural and endovascular, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patrick M McCarthyDivision of Cardiac Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine and Northwestern Medicine, Chicago, Ill.
Roxana MehranThe Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
Marc GerdischDepartment Cardiothoracic Surgery, Franciscan Health Indianapolis, Indianapolis, Ind.
Basel RamlawiDepartment of Cardiac Surgery, Lankenau Heart Center, Mainline Health, Wynnewood, Pa.
Randall J LeeDepartment of Cardiac Electrophysiology, University of California, San Francisco, San Francisco, Calif.
Michael A FergusonHealthcare Economics and Reimbursement, AtriCure, Mason, Ohio.
Jane KruseDivision of Cardiac Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine and Northwestern Medicine, Chicago, Ill.
Richard P WhitlockDivision of Cardiac Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study assessed the influence of surgical left atrial appendage exclusion (LAAE) during cardiac surgery in patients with no preoperative history of atrial fibrillation (AF). Methods: Real World Data Insights, an all-payers' claims database, with approximately 90% Medicare patients was utilized. Patients with no preoperative history of AF (older than age 65 years) undergoing open coronary artery bypass or valve procedures with/without concomitant surgical LAAE with an epicardial clip between 2015 and 2020 and a minimum of 2-year follow-up were included. Inverse probability treatment weighting and logistic regression were used. Results: Open coronary artery bypass represented 48.8% (n = 29,954) and valve 51.2% (n = 31,466) of procedures after adjustment. Thirty-day postoperative AF was present in 12.2% patients (n = 175) for LAAE and 5.8% (n = 3485) for no-LAAE ( Conclusions: LAAE during open cardiac surgery in patients without AF was safe, associated with higher postoperative AF, and lower ischemic stroke and all-cause mortality. Randomized controlled studies are ongoing in a similar population.

Indexed as

atrial fibrillationcardiac surgeryepicardialleft atrial appendage exclusionprophylacticstroke

Identifiers

PMID42305377
PMCPMC13244711

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.