ArticleArchives of medical science : AMS2026
Sleep duration may not have any effect on the risk of stroke: insights from Mendelian randomization and prospective cohort studies.
Article in Archives of medical science : AMS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Association of ophthalmic diseases with stroke: cohort study and Mendelian randomization analysis.Archives of medical science : AMS · 2026Article
- The Relationship between Sleep Duration and Stroke Risk: The Mediating Role of Physical Activity.Brain sciences · 2022Article
- Mediating effects of sleep duration on the association between natural menopause and stroke risk among Chinese women.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Due to contentious associations between sleep and stroke risk, we performed a meta-analysis of cohort studies and Mendelian randomization (MR) analysis. Material and methods: For the meta-analysis, we pooled prospective studies and reviewed the largest genome-wide association studies investigating self-reported or accelerometer-derived sleep duration in relation to stroke subtype: ischemic (IS), cardioembolic (CES), large artery (LAS), or small vessel (SVS). The inverse-variance weighted method (IVW), weighted median (WM)-based method, MR-Egger and MR-Pleiotropy RESidual Sum and Outlier (PRESSO) were performed. To determine the impact of single nucleotide polymorphisms (SNPs), the leave-one-out method was applied. Results: Pooled prospective studies demonstrated that both shorter (< 7 h) [ Conclusions: The meta-analysis suggested that shorter and longer sleep may be associated with increased total stroke risk, although these findings were subject to high heterogeneity. In contrast, the MR analysis did not provide evidence of causal associations between sleep duration and stroke risk in this dataset.
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