Evidence map›Paper›PMID 42305322›Full record

ArticleArchives of medical science : AMS2026

Comparison of the efficacy of vindesine and leurocristine for pediatric acute lymphoblastic leukemia and their effects on quality of life.

Xiaowei Shi, Pisheng Zhang, Xiaohong Du, Lieguang Chen, Shuangyue Li, Zheng Fan

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaowei ShiDepartment of Hematology, Yinzhou People's Hospital, Ningbo City, Zhejiang Province, China.
Pisheng ZhangDepartment of Hematology, Yinzhou People's Hospital, Ningbo City, Zhejiang Province, China.
Xiaohong DuDepartment of Hematology, Yinzhou People's Hospital, Ningbo City, Zhejiang Province, China.
Lieguang ChenDepartment of Hematology, Yinzhou People's Hospital, Ningbo City, Zhejiang Province, China.
Shuangyue LiDepartment of Hematology, Yinzhou People's Hospital, Ningbo City, Zhejiang Province, China.
Zheng FanDepartment of Hematology, Yinzhou People's Hospital, Ningbo City, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The present study aimed to compare the efficacy of vindesine with that of leurocristine for pediatric acute lymphoblastic leukemia and their effects on the quality of life. Material and methods: We included 94 patients with pediatric acute lymphoblastic leukemia admitted to our hospital for treatment and categorized them into two groups: treatment with vindesine (group A, Results: Group A showed no significant difference in the total efficacy rate and 5-year overall survival after treatment ( Conclusions: Although no significant difference was observed between vindesine and leurocristine in treating pediatric acute lymphoblastic leukemia, patients administered vindesine had fewer adverse reactions, shorter length of hospital stay, lower medical expenses, and higher quality of life than those administered leurocristine, indicating a potential association with decreased serum IL-6 and TNF-α expression.

Indexed as

interleukin 6leurocristinepediatric acute lymphoblastic leukemiaquality of lifetumour necrosis factor-αvindesine

Identifiers

PMID42305322
PMCPMC13266739

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.