Evidence map›Paper›PMID 42305312›Full record

ArticleArchives of medical science : AMS2026

Association of micronuclei frequency and other nuclear anomalies with flaxseed diet in metabolic syndrome patients.

José de Jesús López-Jiménez, Alina García-Ruvalcaba, Ana Cecilia Méndez-Magaña, Claudia Elizabeth Granados-Manzo, Lizet Yadira Rosales-Rivera, Elisa García-Morales, Priscila Ayala-Buenrostro, Lorena Viridiana De Alba-Espinoza, Ana Carolina Ángel-Del Río, Fabian Gaona-Sánchez and 1 more

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

José de Jesús López-JiménezDepartamento de Disciplinas Filosófico, Metodológico e Instrumentales; Departamento de Morfología. Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdG); División de Medicina Molecular, Centro de Investigación Biomédica de Occidente (CIBO)-IMSS. Guadalajara, Jalisco, México.
Alina García-RuvalcabaDepartamento de Enfermería Clínica Aplicada (DECA), CUCS, UdG, Guadalajara, Jalisco, México.
Ana Cecilia Méndez-MagañaDepartamento de Salud Pública, CUCS, UdG. Guadalajara, Jalisco, México; Unidad de Medicina Familiar No. 51, Delegación Jalisco, Instituto Mexicano del Seguro Social, Zapopan, Jalisco, México.
Claudia Elizabeth Granados-ManzoServicio de Nutrición Clínica, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, México.
Lizet Yadira Rosales-RiveraInstituto de Terapéutica Experimental y Clínica, Departamento de Fisiología, CUCS, UdG. Guadalajara, Jalisco, México.
Elisa García-MoralesServicio de Neonatología, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, México.
Priscila Ayala-BuenrostroUniversidad del Valle de México, Zapopan, Jalisco, México.
Lorena Viridiana De Alba-EspinozaCoordinación de Planeación, CUCS, UdG. Guadalajara, Jalisco, México.
Ana Carolina Ángel-Del RíoDepartamento de Ingeniería Química y Bioquímica, Instituto Tecnológico de Jiquilpan. Jiquilpan, Michoacán, México.
Fabian Gaona-SánchezDepartamento de Ingeniería Química y Bioquímica, Instituto Tecnológico de Jiquilpan. Jiquilpan, Michoacán, México.
Ana Lilia Fletes-RayasDepartamento de Enfermería Clínica Aplicada (DECA), CUCS, UdG, Guadalajara, Jalisco, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aimed to investigate whether a rich flaxseed diet could modify the micronuclei frequency, nuclear anomalies and biochemical and anthropometric parameters in metabolic syndrome patients. Material and methods: Fifty-eight patients with metabolic syndrome were dichotomized into two groups, namely, the control group (CG) and the intervention group (IG), and the patients in the IG received a diet supplemented with flaxseed. The anthropometric and clinical parameters were measured. Nuclear anomalies isolated from the oral mucosa were analyzed at the beginning and end of the 3-month follow-up. Results: After the nutritional follow-up, the percentage of fat was decreased in the CG (before, 45.40%; after, 37.89%, Conclusions: The group that consumed a diet supplemented with flaxseed showed greater decreases in weight, body mass index and very-low-density lipoprotein than the CG. The numbers of nuclear anomalies were decreased in both groups, but greater mean decreases in micronuclei and binuclear cells were observed in the IG after 3 months.

Indexed as

biochemical markerscardiovascular diseases/prevention and controldiet therapyDNA damage

Identifiers

PMID42305312
PMCPMC13266511

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.