ArticleJournal of clinical practice and research2026
Do Sexually Transmitted Infections Coexist? Evidence from Human Immunodeficiency Virus and Syphilis Coinfection in a Tertiary Care Center.
Article in Journal of clinical practice and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Syphilis and human immunodeficiency virus (HIV) are sexually transmitted infections that share common risk factors and may facilitate each other's transmission. This study aimed to evaluate the frequency of syphilis coinfection among individuals living with HIV over a five-year period. Materials and Methods: In this retrospective study, anti-HIV, rapid plasma reagin (RPR), Results: Among 200 individuals living with HIV, 162 underwent syphilis testing. Of these, 85.5% were male. Syphilis seropositivity was detected in 41 patients (25.3%), including 24 (14.8%) with active infection and 17 (10.5%) with past infection. No significant differences were observed based on age, sex, or year (p>0.05). During the same period, syphilis seropositivity among HIV-negative individuals was 0.96%. HIV positivity was strongly associated with syphilis seropositivity (OR: 34.8; 95% CI: 23.1-52.6; p<0.001). Conclusion: The high rate of syphilis seropositivity among HIV-positive individuals underscores the importance of routine screening at diagnosis and during follow-up.
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