ArticleFrontiers in endocrinology2026
Clinical outcomes of co-transfer of partially and fully compacted morula versus fully compacted morula alone on day 4.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the impact of day 4 double embryo transfer (DET) with a fully compacted morula (FCM) and a partially compacted morula (PCM) versus day 4 single embryo transfer (SET) with an FCM on clinical and neonatal outcomes in fresh cycles. Methods: This was a retrospective cohort study including 889 fresh day 4 embryo transfer cycles conducted between October 2018 and December 2024. Propensity score matching (PSM) was applied to control for potential confounders and compare the clinical outcomes between SET with FCM and DET with FCM and PCM. Results: After PSM, logistic regression analysis showed no significant differences in clinical pregnancy rate (CPR), miscarriage rate, live birth rate (LBR), cumulative live birth rate (CLBR), monozygotic twin rate, stillbirth rate, and cesarean section rate (CSR) (all Conclusion: In fresh cycles, there were no significant differences in CPR, LBR and CLBR following day 4 DET with FCM and PCM compared with SET with FCM. However, the MPR was significantly higher in the DET group. SET with FCM may be a preferable strategy for balancing clinical and multiple pregnancy rates.
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