Evidence map›Paper›PMID 42305253›Full record

ArticlePeerJ2026

Association between TyG index, TG/HDL-C ratio and coronary heart disease risk in elderly postmenopausal women: a retrospective cohort study.

Wei Wen, Qing Ye, Lixiang Zhang

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Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Wei Wen *Department of Cardiology, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei City, Anhui Province, China.
Qing Ye *Department of Cardiology, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei City, Anhui Province, China.
Lixiang ZhangDepartment of Cardiology, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei City, Anhui Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to explore the importance of the triglyceride-glucose (TyG) index and triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) ratio in predicting the risk of coronary heart disease (CHD) in elderly postmenopausal women. Methods: This was a retrospective cohort study conducted from March 2018 to February 2019. A total of 749 natural menopausal elderly women aged ≥60 years who were hospitalized in the Department of Cardiology, First Affiliated Hospital of the University of Science and Technology of China and underwent coronary angiography for the first time were divided into CHD group (527 patients) and non-CHD group (222 patients). The clinical data parameters used in this analysis were chosen based on literature support and clinical findings related to CHD in elderly postmenopausal women. The clinical data of the two groups were compared, and the predictive value of the TyG index and TG/HDL-C was analyzed by m ultivariable logistic regression analysis and the receiver operating characteristic (ROC) curves. Results: Multivariable logistic regression analysis showed that hemoglobin (Hb), high-sensitivity C-reactive protein (hs-CRP), TyG index, TG/HDL-C, daily sleep duration and glycosylated hemoglobin (HbA1c) were independent influencing factors of CHD in elderly postmenopausal women ( Conclusion: This study demonstrates that the TyG index and TG/HDL-C ratio are significantly associated with CHD risk in elderly postmenopausal women, as evidenced by their acceptable predictive performance (AUC: 0.740-0.771) and independent statistical significance (

Indexed as

Blood GlucoseCholesterol, HDLCoronary DiseasePostmenopauseTriglyceridesAgedChinaCoronary AngiographyC-Reactive ProteinFemaleGlycated HemoglobinHumansMiddle AgedRetrospective StudiesRisk FactorsROC CurveBlood GlucoseCholesterol, HDLC-Reactive ProteinGlycated HemoglobinTriglyceridesCoronary angiographyCoronary heart diseaseMenopausePredictionTriglyceride glucose index

Identifiers

PMID42305253
PMCPMC13267789

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.