Evidence map›Paper›PMID 42305219›Full record

ArticleACS medicinal chemistry letters2026

Semisynthesis of Mycothiazole Analogs having Distinct Bioactivity.

Jacqueline G Clarke, Naibedya Dutta, Matthew S Nickel, Zhang Wang, Juri Kim, Joseph Media, David A Coppage, Erin P McCauley, Joe A Gerke, Marc O Anderson and 4 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jacqueline G ClarkeDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.ORCID https://orcid.org/0009-0009-2467-9701
Naibedya DuttaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Matthew S NickelDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Zhang WangInstitute for Psychedelics and Neurotherapeutics, University of California Davis, Davis, California 95616, United States.ORCID https://orcid.org/0000-0001-5659-0036
Juri KimLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Joseph MediaDivision of Hematology and Oncology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, United States.
David A CoppageDepartment of Chemistry, University of California Davis, One Shields Ave, Davis, California 95616, United States.
Erin P McCauleyDepartment of Chemistry and Biochemistry, California State University Dominguez Hills, Carson, California 90747, United States.
Joe A GerkeDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Marc O AndersonDepartment of Chemistry and Biochemistry, San Francisco State University, San Francisco, California 94132, United States.ORCID https://orcid.org/0000-0002-1233-3801
Ryo Higuchi-SanabriaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Frederick A ValerioteDivision of Hematology and Oncology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, United States.
Phillip CrewsDepartment of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California 95064, United States.ORCID https://orcid.org/0000-0002-9061-9549
Tyler A JohnsonDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.ORCID https://orcid.org/0000-0001-6816-726X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Semisynthetic modification of mycothiazole (

Indexed as

cancer cell linesC. elegansdiastereomersdienemycothiazole

Identifiers

PMID42305219
PMCPMC13266639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.