ArticleACS medicinal chemistry letters2026
Development of a High-Throughput Experimentation Workflow for Photochemical Reaction Screening.
Article in ACS medicinal chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Commercially available lab equipment was successfully integrated to enable visible-range photochemistry in a high-throughput 96-well screening format with magnetic stirring. Precise temperature control with maximal throughput was achieved by positioning the light source above the reaction mixtures and a cooling source below. This platform was benchmarked against other state-of-the-art commercial options using the Doyle-MacMillan reaction. Establishing a highly irradiated, temperature-controlled micromole-scale high-throughput experimentation (HTE) reaction screening protocol in a standard 96-well format could potentially accelerate modern reaction optimization in both medicinal and process chemistry.
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