ArticleIntegrative organismal biology (Oxford, England)2026
You Should Look a Gift Ungulate in the Mouth: Using 2D Occlusal Cheek Tooth Morphology to Study the Evolution of Molarization in Ungulates.
Article in Integrative organismal biology (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cheek teeth are filled to the cusp with information about mammalian evolution. Studying the evolution of mammalian cheek tooth crown complexity has benefited our understanding of mammalian evolution in developmental, morphological, and ecological contexts. Most work is focused on individual cheek tooth loci as opposed to considering the premolars and molars as serial homologues. This focus on individual tooth loci has left the exploration of inter-regional phenomena understudied. One such phenomenon is the molarization of premolars across hoofed mammals; some have simple unicuspid premolars while others have premolar crowns that are equal in complexity to their molars. Many developmental models have been proposed to understand cheek tooth evolution, but minimal work has been done to synthesize these models into a holistic understanding of cheek tooth crown complexity evolution. We investigated if applying a synergized theoretical framework of the inhibitory and patterning cascade model to artiodactyl and perissodactyl taxa could be used to study the evolution of molarization in hoofed mammals. We applied an existing 2D landmarking scheme for the upper and lower premolar molar boundaries of hoofed mammals to capture the morphology across this important identity boundary. Shape data were analyzed through phylogenetically informed modularity analyses to capture the covariation structure at the upper and lower premolar-molar boundaries. A-priori modularity hypotheses were proposed based on developmental models including the patterning cascade model and the inhibitory cascade model. Both artiodactyl and perissodactyl results showed support for modularity across the upper and lower premolar molar boundary but showed more variation in the upper premolar molar boundary. Artiodactyls show consistency in support for modularity hypotheses between upper and lower premolar molar boundaries where perissodactyls show significant differences in support for modularity hypotheses between upper and lower premolar molar boundaries. Our results illustrate that the covariation structure at the premolar molar boundary has convergent and divergent elements that both have consequences for our understanding of the evolution of molarization within and between artiodactyls and perissodactyls.
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