Evidence map›Paper›PMID 42305168›Full record

ArticleJTCVS structural and endovascular2025

The perfect match: Aortic valve sizing to maximize hemodynamic performance and survival.

Barbara C S Hamilton, Shinichi Fukuhara, Michael Boulware, Robert B Hawkins, Sachin S Goel, Bo Yang, Himanshu J Patel, Gorav Ailawadi, Stanley J Chetcuti, Shuzhen Li and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JTCVS structural and endovascular, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Surgical Information Available on the Box of Cardiac Valve Prostheses Remains Inadequate.Interdisciplinary cardiovascular and thoracic surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Barbara C S HamiltonDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.
Shinichi FukuharaDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.
Michael BoulwareCardiac Surgery Clinical Research and Medical Science, Medtronic, Mounds View, Minn.
Robert B HawkinsDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.
Sachin S GoelDepartment of Cardiovascular Surgery and Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, Tex.
Bo YangDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.
Himanshu J PatelDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.
Gorav AilawadiDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.
Stanley J ChetcutiDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.
Shuzhen LiCardiac Surgery Clinical Research and Medical Science, Medtronic, Mounds View, Minn.
Mikhale GrundtnerCardiac Surgery Clinical Research and Medical Science, Medtronic, Mounds View, Minn.
Julie A LinickCardiac Surgery Clinical Research and Medical Science, Medtronic, Mounds View, Minn.
Michael J ReardonDepartment of Cardiovascular Surgery and Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, Tex.
G Michael DeebDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We assessed the value of using a size ratio of implanted valve opening diameter to native annular diameter to determine postoperative hemodynamics and survival after surgical aortic valve replacement. Methods: In total, 1519 patients from 3 trials had a preoperative computed tomography scan. A size ratio was created using the implanted valve's Ebels' prosthetic valve-derived effective diameter (ED) and the patient's computed tomography perimeter-derived native annular diameter (CTD). Restricted cubic spline curves showed the association between size ratio and hemodynamic performance. Patients were divided into 3 ratio groups: <80%, 80% to 90%, and >90%. Hemodynamic performance was evaluated yearly for 5 years. Multivariable proportional hazard regression examined the association between size ratio and 5-year survival. Results: Mean valve gradient, peak velocity, effective orifice area (EOA), indexed EOA, dimensionless velocity index, and prosthesis-patient mismatch were significantly better advancing from the 80% to the 90% groups ( Conclusions: An ED/CTD size ratio >90% is associated with optimal postoperative hemodynamic performance and improved 5-year survival. Preoperative ED/CTD ratio provides the ideal implanted valve size and helps determine if annular enlargement is necessary.

Indexed as

annular enlargementaortic valve sizingCT scan perimeter-derived aortic annular diameter (CTD)Ebels' effective diameter (ED)size ratio matchsurgical aortic valve replacement

Identifiers

PMID42305168
PMCPMC13244681

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.