Evidence map›Paper›PMID 42304947›Full record

ArticlePest management science2026

Piperidine-functionalized formononetin derivatives: Design, synthesis and evaluation of antibacterial activity, modes and phenotypes.

Miaohe Zhang, Junrong Song, Xian Wei, Gefei Hao, Linhong Jin, Barana C Jayawardana, Buddhi Marambe, Shuang Feng, Wei Xue

Abstract read
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miaohe ZhangSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang, People's Republic of China.
Junrong SongCenter for R&D of Fine Chemicals, Guizhou University, Guiyang, People's Republic of China.
Xian WeiSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang, People's Republic of China.
Gefei HaoCenter for R&D of Fine Chemicals, Guizhou University, Guiyang, People's Republic of China.ORCID https://orcid.org/0000-0003-4090-8411
Linhong JinCenter for R&D of Fine Chemicals, Guizhou University, Guiyang, People's Republic of China.ORCID https://orcid.org/0000-0002-2210-3831
Barana C JayawardanaDepartment of Animal Science, Faculty of Agriculture, University of Peradeniya, Peradeniya, Sri Lanka.
Buddhi MarambeDepartment of Crop Science, Faculty of Agriculture, University of Peradeniya, Peradeniya, Sri Lanka.
Shuang FengSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang, People's Republic of China.
Wei XueCenter for R&D of Fine Chemicals, Guizhou University, Guiyang, People's Republic of China.ORCID https://orcid.org/0000-0003-4471-5414

Funding

National Key Research and Development Program of China 2024YFE0214300Natural Science Foundation of Guizhou Province QKHJC-MS[2026]240Natural Science Foundation of Guizhou Province QKHJC-MS[2026]388
6 · The paper itself

Abstract

backgroundPlant pathogenic bacteria severely impact crop yield and quality. Long-term use of conventional bactericides has led to resistance, and raised environmental and food safety concerns, necessitating new, efficient and eco-friendly agents.

resultsThis study designed and synthesized a series of novel piperidine-functionalized formononetin derivatives (N1-N42) and evaluated their antibacterial activity. In vitro assays showed that several compounds strongly inhibited Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac). Notably, thiourea-piperidine N30 and piperidine hydrochloride N42 were highly effective against Xoo, with median effective concentration (EC

conclusionN30 and N42 have good potential to be developed as formononetin-based antibacterial agents. © 2026 Society of Chemical Industry.

Indexed as

Anti-Bacterial AgentsIsoflavonesPiperidinesXanthomonasOryzaPlant DiseasesAnti-Bacterial AgentsformononetinIsoflavonesPiperidinesantibacterial activityantibacterial modesantibacterial phenotypesformononetin derivativespiperidine functionalization

Identifiers

PMID42304947
PMCPMC13569255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.