Evidence map›Paper›PMID 42304814›Full record

ArticlePhysiological reports2026

Platelet glycoprotein VI modulates leukocyte characteristics in sepsis-induced systemic inflammatory response in male mice.

Adam Corken, Jerry Ware, Keshari M Thakali

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adam CorkenDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0002-4700-9091
Jerry WareDepartment of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Keshari M ThakaliDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0002-6799-1203

Funding

HHS | National Institutes of Health (NIH) 5R21AI133160-02
6 · The paper itself

Abstract

Platelets are responsible for maintaining vascular integrity through the process of hemostasis with glycoprotein VI (GPVI) acting as a major receptor for platelet activation. Interestingly, platelet participation in inflammation is an evolving concept with few studies exploring GPVI in the framework of inflammation and even less in the context of the most severe inflammatory condition: sepsis. Here we utilized a GPVI deficient mouse model (GPVI

Indexed as

Blood PlateletsLeukocytesPlatelet Membrane GlycoproteinsSepsisSystemic Inflammatory Response SyndromeAnimalsMaleMiceMice, Inbred C57BLMice, KnockoutNeutrophilsPlatelet AdhesivenessTumor Necrosis Factor-alphaPlatelet Membrane Glycoproteinsplatelet membrane glycoprotein VITumor Necrosis Factor-alphaGPVIinflammationleukocytesplateletssepsis

Identifiers

PMID42304814
PMCPMC13273020

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.