Evidence map›Paper›PMID 42304549›Full record

ArticlePest management science2026

Resistance monitoring and putative biochemical mechanisms of Spodoptera frugiperda to different insecticides in China.

Huanhuan Wang, Shiyuan Hu, Rui Zhao, Yuelong Li, Yuxian Liu, Shiyang Xie, Zhenyu Li, Pei Liang, Shaohua Gu

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Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Huanhuan WangKey Laboratory of Green Prevention and Control on Fruits and Vegetables in South China Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of High Technology for Plant Protection, Plant Protection Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Shiyuan HuState Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, China.
Rui ZhaoXuzhou Vocational College of Bioengineering, Xuzhou, China.
Yuelong LiState Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, China.
Yuxian LiuState Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, China.
Shiyang XieSanya Institute of China Agricultural University, Sanya, China.
Zhenyu LiKey Laboratory of Green Prevention and Control on Fruits and Vegetables in South China Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of High Technology for Plant Protection, Plant Protection Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Pei LiangState Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, China.
Shaohua GuState Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0001-9481-2015

Funding

National Key Research and Development Program of China
6 · The paper itself

Abstract

backgroundThe control of the fall armyworm (FAW), Spodoptera frugiperda, relies heavily on insecticides, which has accelerated the evolution of resistance; thus it is urgent to monitor the insecticide resistance status of this pest.

resultsIn this study, insecticide bioassays were conducted using the topical application method on 16 field populations collected in China in 2023. The results showed that FAW in China is susceptible to emamectin benzoate, chlorantraniliprole, tetrachlorantraniliprole and lambda-cyhalothrin, whereas some populations exhibited low-level resistance to indoxacarb, spinetoram, broflanilide, chlorfenapyr and acephate. No mutations were detected in the target genes GluCl, nAChR, RyR, GABAR and VGSC; however, 67.7% individuals displayed mutations at locus F290V of ace-1. Detoxification enzyme activity and synergistic assays suggest that cytochrome P450 enzymes (P450s), glutathione S-transferases (GSTs) and esterases (ESTs) are implicated in the low-level resistance to indoxacarb, spinetoram and acephate. GSTs and ESTs also contributed to broflanilide resistance, whereas only GSTs played a role in chlorfenapyr resistance.

conclusionOur study offers substantial insights for monitoring and managing the development of insecticide resistance in S. frugiperda populations in China. Future research will be needed to further investigate the metabolic mechanisms of related detoxifying enzymes and the resistance mechanisms mediated by ace-1 mutations. © 2026 Society of Chemical Industry.

Indexed as

Insecticide ResistanceInsecticidesSpodopteraAnimalsChinaInsect ProteinsLarvaInsecticidesInsect Proteinscross‐resistancedetoxifying enzymefall armyworminsecticide resistancemutation frequencyresistance mechanisms

Identifiers

PMID42304549
PMCPMC13569315

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