Evidence map›Paper›PMID 42304419›Full record

ArticleJournal of nanobiotechnology2026

A SIRT1-stabilizing nanofibrous platform via suppression of ubiquitination for enhanced diabetic wound healing: synergistic therapy with saracatinib and MOF-818.

Pingping Xue, Zhi Yin, Yuhang Chen, Anran Zhang, Chenyu Zhuo, Hai Du, Nuo Xu, Renqun Mao, Xiaofan Yang

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pingping Xue *Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zhi Yin *Department of Dermatology, The first Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China.
Yuhang ChenDepartment of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Anran ZhangDepartment of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Chenyu ZhuoDepartment of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Hai DuDepartment of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Nuo XuDepartment of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Renqun MaoDepartment of Hand and Foot Surgery, Shenzhen Nanshan People's Hospital, Shenzhen, 518052, China. wufeng5408@163.com.
Xiaofan YangDepartment of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. 2017XH0119@hust.edu.cn.

Funding

National Natural Science Foundation of China 82301591the Health Science and Technology Planning Project of Shenzhen Nanshan District NS2024038the Medical Science and Technology Research Foundation of Guangdong Province B2024010the Special Key Project of Technological Innovation and Application Development of Chongqing CSTB2025TIAD-KPX0095
6 · The paper itself

Abstract

Chronic diabetic wounds, characterized by persistent oxidative stress, dysregulated inflammation, impaired angiogenesis, and susceptibility to bacterial infection, present a significant clinical challenge due to delayed tissue repair. This study reports the development of a multifunctional nanofibrous dressing, termed P-G

Indexed as

NanofibersQuinazolinesSirtuin 1Wound HealingAnimalsAnti-Bacterial AgentsDiabetes Mellitus, ExperimentalDrug SynergismHumansMaleOxidative StressRatsRats, Sprague-DawleyReactive Oxygen SpeciesUbiquitinationAnti-Bacterial AgentsQuinazolinesReactive Oxygen SpeciesSirtuin 1Chronic diabetic woundsMOFNanofiberOxidative stressSIRT1

Identifiers

PMID42304419
PMCPMC13523385

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.