ArticleBMC pregnancy and childbirth2026
Maternal age differences among women with histologically diagnosed molar pregnancy.
Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo determine the occurrence of molar pregnancies across maternal age groups and to examine βhCG levels at admission and follow-up.
methodsA retrospective cohort study conducted between the years 2014-2021. Included women with a pathology-diagnosed partial or complete mole. Demographic, clinical and laboratory data of women with a molar pregnancy, ≤ 40 or > 40 years were compared. Long-term follow-up data after surgical evacuation and βhCG levels were collected.
resultsA total of 115 cases of complete (n = 15) or partial moles (n = 100) during the study period were included. Women's ages ranged from 16 to 55 years (mean 33.3 ± 8.2). Most participants, 73 (63.5%) were 20-35 years. Compared to women > 40 years (n = 23), women ≤ 40 (n = 92) partial moles were more common in the ≤ 40 group (85 [92.4%] vs. 15 [65.2%], p = 0.001), while complete moles were more frequent in the > 40 group (8 [34.8%] vs. 7 [7.6%], p = 0.001), even after controlling for age, gravidity, and parity (p = 0.005, OR 6.5). βhCG levels over time were followed with follow-up ranged from 30 to 203 days. βhCG levels normalized within 3 months in 90% of cases, with the largest decrease occurred after the first month. Gestational trophoblastic neoplasia (GTN) occurred in 7 (6.1%) cases, with no age group differences.
conclusionsThis study emphasis that molar pregnancies affect a wide age range. Furthermore, it confirms a positive long-term prognosis.
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