Evidence map›Paper›PMID 42304289›Full record

ArticleBMC primary care2026

Integrated holistic chronic wound care package for skin-NTDs and other conditions for the primary healthcare setting in Ethiopia.

Tigest Ajeme, Oumer Ali, Agumasie Semahegn, Asrat Mengiste, Eiman Siddig Ahmed, Mersha Kinfe, Selamawit G Kebede, Stephen Bremner, Vasso Anagnostopoulou, Malcolm Brewster and 3 more

Abstract read
In one paragraph

Article in BMC primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tigest AjemeCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia. tgabysinia@gmail.com.ORCID 0000-0002-4725-6367
Oumer AliCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Agumasie SemahegnCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Asrat MengisteCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Eiman Siddig AhmedCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, University of Brighton, University of Sussex, Brighton, BN1 9PX, UK.
Mersha KinfeCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Selamawit G KebedeCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Stephen BremnerDivision of Methodologies, Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.
Vasso AnagnostopoulouCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, University of Brighton, University of Sussex, Brighton, BN1 9PX, UK.
Malcolm BrewsterFerry Road Health Centre, Rye, East Sussex, UK.ORCID 0000-0003-1093-6382
Gail DaveyCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, University of Brighton, University of Sussex, Brighton, BN1 9PX, UK.
Abebaw FekaduCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Maya SemrauCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, University of Brighton, University of Sussex, Brighton, BN1 9PX, UK.

Funding

National Institute for Health and Care Research 131996, UK International Development Funding from the UK Government to support global health research
6 · The paper itself

Abstract

backgroundGlobally, chronic wounds resulting from diverse etiologies impose a significant physical, psychosocial, and economic burden and have remained a highly neglected public health challenge. Yet, people in rural Ethiopia have limited access to quality and comprehensive wound care. There is a marked paucity for an integrated, holistic care model in the primary healthcare settings. Hence, this study aimed to develop a context-tailored, integrated, holistic, chronic wound care package in Ethiopia.

methodsA multi-method approach was applied, including a scoping review, formative assessments, Theory of Change workshops and a qualitative validation study. Purposive sampling was employed to recruit participants. Collected data were transcribed, coded, and thematically analysed to generate insights for refining the intervention package.

resultsA total of 49 stakeholders participated in the Theory of Change (ToC) workshops, while 36 participants were included in the qualitative study. The intervention package is structured around six core thematic components: awareness-raising and stigma reduction, capacity-building, active case detection and follow-up, program and supply chain management, Institutional and community-based rehabilitation, monitoring, and evaluation. Implementation and scale-up of these components are designed to cascade across three levels of the existing primary healthcare system, specifically the health organization, the health facility level, and the community level.

conclusionThis study introduced a context-driven, integrated, and holistic wound care package aimed at managing chronic wounds alongside their associated mental health and psychosocial challenges. The package encompasses interventions that address the physical, psychological, and social impacts of chronic wounds in individuals affected by neglected tropical diseases of the skin and related conditions. It employs multilevel implementation strategies targeting individuals, communities, and the health system to reduce morbidity, disability, and the economic and psychosocial burdens linked to chronic wounds. This standardized, scalable, and sustainable care model provides a promising approach for Ethiopia and other low- and middle-income countries.

Indexed as

Delivery of Health Care, IntegratedHolistic HealthNeglected DiseasesPrimary Health CareWounds and InjuriesChronic DiseaseEthiopiaHumansQualitative ResearchChronic woundsDelivery of health care, integratedEthiopiaNeglected tropical diseasesPrimary health care

Identifiers

PMID42304289
PMCPMC13281334

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.