Evidence map›Paper›PMID 42304188›Full record

ReviewAllergy2026

Remission in Global Airway Diseases: EUFOREA Consensus Paper.

J Christian Virchow, Xander Bertels, Vibeke Backer, Benjamin S Bleier, Marco Caminati, Diego M Conti, Eugenio De Corso, Mina Gaga, Valerie J Lund, Corrado Pelaia and 13 more

Abstract readConsensus StatementReview
In one paragraph

Review in Allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

J Christian VirchowKlinik für Pneumologie, Allergologie und Internistische Intensivmedizin, Department für Innere Medizin, Universitätsmedizin Rostock, Rostock, Germany.ORCID https://orcid.org/0000-0003-4291-1956
Xander BertelsEuropean Forum for Research and Education in Allergy and Airway Diseases (EUFOREA), Brussels, Belgium.ORCID https://orcid.org/0000-0002-4815-9067
Vibeke BackerDepartment of Otorhinolaryngology, Head & Neck Surgery, and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-7806-7219
Benjamin S BleierDepartment of Otolaryngology-Head and Neck Surgery, Mass Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-0783-8861
Marco CaminatiAllergy Unit and Asthma Center, Integrated University Hospital of Verona and Department of Medicine, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0001-7383-1487
Diego M ContiEscuela de Doctorado UAM, Centro de Estudios de Posgrado, Universidad Autónoma de Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0002-8896-495X
Eugenio De CorsoUOC Otorinolaringoiatria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.ORCID https://orcid.org/0000-0001-5761-7018
Mina Gaga1st Respiratory Medicine Department, Hygeia Hospital, Marousi, Greece.ORCID https://orcid.org/0000-0002-9949-6012
Valerie J LundProfessor Emeritus in Rhinology, University College London, London, UK.ORCID https://orcid.org/0000-0002-2503-2215
Corrado PelaiaDepartment of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Catanzaro, Italy.ORCID https://orcid.org/0000-0002-4236-7367
Anju T PetersDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-0745-2379
Glenis K ScaddingENT Department, Royal National ENT Hospital, London, UK.ORCID https://orcid.org/0000-0002-0732-9728
Martin WagenmannDepartment of Otorhinolaryngology, Düsseldorf University Hospital (UKD), Düsseldorf, Germany.ORCID https://orcid.org/0000-0002-9734-0241
Riyad O Al-LehebiDepartment of Pulmonology, King Fahad Medical City, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-3232-6668
Guy G BrusselleDepartment of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0001-7021-8505
Philippe GevaertUpper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.ORCID https://orcid.org/0000-0002-1629-8468
Liam G HeaneyWellcome-Wolfson Institute for Experimental Medicine, Queens University Belfast, Belfast, UK.ORCID https://orcid.org/0000-0002-9176-5564
Stella E LeeDepartment of Otolaryngology - Head & Neck Surgery, Mass General Brigham, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-6563-6606
Florence SchleichExercise Physiology Lab, Department of Physical Activity and Rehabilitation Sciences, University of Liège, Liège, Belgium.ORCID https://orcid.org/0000-0002-2678-1373
Frederik TrinkmannDepartment of Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.ORCID https://orcid.org/0000-0001-5877-877X
Peter W HellingsAllergy and Clinical Immunology Research Unit, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0001-6898-688X
Wytske J FokkensDepartment of Otorhinolaryngology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0003-4852-229X
Paola RoglianiUnit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.ORCID https://orcid.org/0000-0001-7801-5040

Funding

AstraZenecaEli Lilly and CompanyGlaxoSmithKlineSanofi-Regeneron
6 · The paper itself

Abstract

The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease-modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR). This EUFOREA consensus aims to establish practical guidance for inducing and maintaining remission in global airway diseases. An international panel of experts in pneumology, rhinology, and allergology convened in Rome (October 2025) to review current evidence and develop consensus statements. The panel achieved consensus on key principles: (i) remission is a therapeutic target independent of disease severity prior to treatment initiation and should not be reserved for severe cases; (ii) CRSwNP with nonallergic eosinophilic asthma, and AR with allergic asthma should be considered features of a single disease rather than comorbidities; (iii) remission should be assessed by each subspecialty separately while warranting combined approaches; (iv) pragmatic definitions prioritizing achievability and clinical utility are recommended; and (v) a 4-week recall window is preferred to assess symptom control within the evaluation of remission and a 12-month period is suggested as the minimal period to define remission. Remission represents an ambitious yet achievable goal, with practical guidance for optimizing patient outcomes.

Indexed as

Respiratory Tract DiseasesChronic DiseaseHumansRemission InductionRhinosinusitisallergic rhinitisasthmachronic rhinosinusitisglobal airway diseasesremission

Identifiers

PMID42304188
PMCPMC13569676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.