Evidence map›Paper›PMID 42303978›Full record

ArticleBlood cancer journal2026

Detection of MEN1 resistance mutations in cell-free DNA from acute leukemia patients treated with menin inhibitors.

Neerav Shukla, Karmelina Charalambous, Shanita Li, Kaitlyn H Ko, Hilary Casanova, Eric Buehler, Cassidy Cobbs, Ruchi Patel, Angela Rose Brannon, Mark D Ewalt and 9 more

Abstract readLetter
In one paragraph

Article in Blood cancer journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Atopic dermatitis.Nature reviews. Disease primers · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Neerav ShuklaDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. shuklan@mskcc.org.ORCID http://orcid.org/0000-0003-2516-2965
Karmelina CharalambousThe Marie Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0009-0002-4658-3777
Shanita LiDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Kaitlyn H KoHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Hilary CasanovaThe Marie Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Eric BuehlerThe Marie Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0009-0004-6354-2015
Cassidy CobbsIntegrated Genomics Operation, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-4465-8894
Ruchi PatelIntegrated Genomics Operation, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Angela Rose BrannonDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mark D EwaltDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-4245-752X
Maria Luisa SulisDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
William L CarrollPerlmutter Cancer Center and Department of Pediatrics, NYU Langone Medical Center, New York, New York, USA.
Maria E ArcilaDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-5824-6554
Neeman MohibullahIntegrated Genomics Operation, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Michael BergerDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ross L LevineHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-7884-1905
Eytan M SteinLeukemia Service, Division of Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ronak ShahThe Marie Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sheng F CaiLeukemia Service, Division of Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA. cais1@mskcc.org.ORCID http://orcid.org/0000-0002-2708-887X

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42303978
PMCPMC13272672

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.