Evidence map›Paper›PMID 42303933›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2026

Intraocular Lens Calculation Concept Based on Aphakic Refraction-Considerations on a Cornea Model With Two Refracting Surfaces.

Achim Langenbucher, Nóra Szentmáry, Alan Cayless, Peter Hoffmann, Jascha Armin Wendelstein

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Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Achim LangenbucherDepartment of Experimental Ophthalmology, Saarland University, Homburg, Germany. achim.langenbucher@uni-saarland.de.ORCID http://orcid.org/0000-0001-9175-6177
Nóra SzentmáryDepartment of Experimental Ophthalmology, Saarland University, Homburg, Germany.
Alan CaylessSchool of Physical Sciences, The Open University, Milton Keynes, UK.
Peter HoffmannAugen- und Laserklinik Castrop-Rauxel, Castrop-Rauxel, Germany.
Jascha Armin WendelsteinDepartment of Experimental Ophthalmology, Saarland University, Homburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop a concept for predicting the power of an intraocular lens (IOL) and the spectacle refraction after cataract surgery based on aphakic refraction (REFa) using vergence transforms with a two-surface cornea model.

methodsThis simulation study is based on a large dataset originally used in IOLCon ( www.IOLCon.org ) for optimising lens constants. Proxy values for REFa calculated from the available information in this dataset were used to develop a strategy for predicting the effective lens position (ELP). A variety of models, including linear, quadratic, sigmoidal and two stepwise linear models, were evaluated. Using this ELP, vergence transform techniques were applied to derive the IOL power for a given target refraction or the spectacle refraction for a given IOL power. This concept was applied to subsets of the IOLCon dataset with the Hoya Vivinex and the Bausch & Lomb enVista lenses to show the efficiency of the calculation.

resultsAfter evaluating the ELP prediction models on the 22,577 IOLCon data, it was decided to use the sigmoidal model for calculating the ELP corrected by a linear term for the A constant. Compared with the fully disclosed Castrop formula, the predicted ELP showed a root-mean-squared deviation of 0.221/0.221 mm with the Vivinex/enVista lens and the predicted IOL power showed a root-mean-squared deviation of 0.369/0.375 D.

conclusionsWhere biometric data for a classical IOL power calculation are unavailable, this vergence-based calculation concept may help to identify the appropriate IOL power and to predict the spectacle refraction after cataract surgery. A clinical study with 'real' REFa measurements is required to validate these results.

Indexed as

AphakiaAphakia, PostcataractCorneaLenses, IntraocularRefraction, OcularCataract ExtractionComputer SimulationHumansModels, BiologicalAphakic refractionELP prediction modelIOL power calculationTwo-surface cornea modelVergence calculation

Identifiers

PMID42303933
PMCPMC13396038

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.