Trial reportSurgical endoscopy2026
Preperitoneal analgesia under direct visualization: laparoscopic-guided deep rectus sheath block improves postoperative pain control after laparoscopic cholecystectomy: a randomized controlled trial.
Trial report in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06976320 (Deep Rectus Sheath Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy), which is not on this map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Deep Rectus Sheath Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy
Who cites it
2 citing papers in PubMed.
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConventional abdominal wall blocks primarily target somatic afferent nerves and may therefore provide limited relief for the peritoneal component of postoperative pain. This study aimed to investigate whether a laparoscopic-guided deep rectus sheath (preperitoneal) block (RSB) could reduce postoperative opioid consumption and improve postoperative pain in patients undergoing laparoscopic cholecystectomy.
methodsPatients were randomly assigned to either the control group or the deep RSB group. In the deep RSB group, the block was performed intraoperatively under direct laparoscopic visualization. No block was performed in the control group. In the deep RSB group, postoperative ultrasound assessment was used to verify bilateral local anesthetic localization. Postoperatively, all patients were connected to an intravenous patient-controlled analgesia device containing morphine. The primary outcome was cumulative morphine consumption within the first 24 postoperative hours.
resultsCumulative 24-h morphine consumption was significantly lower in the deep RSB group, with a median difference of - 9 mg (95% CI - 11 to - 6; p = 0.0001). Pain scores at rest and during movement were significantly lower in the deep RSB group at 2, 6, and 12 h postoperatively, with no significant difference observed at 24 h. Rescue analgesia requirement and incidence of postoperative nausea and vomiting were similar between groups. Quality-of-recovery scores at 24 h were significantly higher in the deep RSB group.
conclusionsLaparoscopic-guided deep RSB significantly reduced postoperative opioid consumption and improved early postoperative pain control after laparoscopic cholecystectomy. Targeting the preperitoneal plane under direct laparoscopic visualization may enhance early multimodal analgesia in these patients. TRIAL REGISTRY: ClinicalTrials.gov identifier: NCT06976320.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.