ArticleOphthalmology and therapy2026
Subfoveal Choroidal Thickness is Independently Associated with Axial Length and Myopia in Preschool Children: A Swept-Source Optical Coherence Tomography Study.
Article in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Evaluation of Posterior Segment Structural and Vascular Changes After Gonioscopy-Assisted Transluminal Trabeculotomy.Diagnostics (Basel, Switzerland) · 2026Article
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6 authors.
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Abstract
introductionThe current study assessed subfoveal choroidal thickness (SFCT) in Chinese preschool children using swept-source optical coherence tomography (OCT) and evaluated its associations with age, sex, axial length, refractive status, family history of myopia, and corneal curvature.
methodsIn this cross-sectional observational study, 303 eyes of 303 preschool children with no ocular diseases underwent comprehensive ophthalmic examinations, including cycloplegic refraction. SFCT was measured using swept-source OCT. Factors affecting changes in SFCT were analyzed using a general linear model.
resultsThe mean SFCT was 326.33 ± 43.01 μm (range 198.67-438.33 μm) in children aged 3-6 years. The myopic group had significantly thinner SFCT than the emmetropic group (305.66 ± 41.18 μm vs. 347.41 ± 33.68 μm; p < 0.05). After adjusting for covariates, SFCT remained significantly lower in the myopic group (317.23 μm vs. 338.42 μm; mean difference: 21.19 μm, 95% confidence interval 7.09-35.28 μm). Myopia significantly affected SFCT (F = 8.75, p = 0.003, η
conclusionIn preschool children, myopia is associated with significantly thinner SFCT, which is independently influenced by spherical equivalent refraction and axial length, but not by age, sex, or family history of myopia. These findings suggest that SFCT may serve as a responsive indicator of early myopic changes in preschoolers, though longitudinal studies are needed to determine its temporal relationship with axial elongation.
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