Evidence map›Paper›PMID 42303888›Full record

ArticleInternal and emergency medicine2026

Thrombocytopenia in carriers and patients with antiphospholipid syndrome: insights from the nationwide START-APS registry.

Francesco Del Sole, Tommaso Bucci, Danilo Menichelli, Emilia Antonucci, Daniela Poli, Vittorio Pengo, Paul R J Ames, Doris Barcellona, Piera Sivera, Attilia Maria Pizzini and 4 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Francesco Del Sole *Department of Anatomical, Histological, Forensic Medicine and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy.
Tommaso Bucci *Internal, Vascular and Emergency Medicine-Stroke Unit, University of Perugia, Perugia, Italy.
Danilo Menichelli *Department of General Surgery, Surgical Specialty and Anesthesiology, Sapienza University of Rome, Rome, Italy.
Emilia AntonucciArianna Anticoagulazione Foundation, Bologna, Italy.
Daniela PoliThrombosis Centre, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Vittorio PengoCardio-Immunology and Thrombosis Research Laboratory, University of Padova, Padua, Italy.
Paul R J AmesDepartment of Haematology, Dumfries Royal Infirmary, Cargenbridge, Dumfries, UK.
Doris BarcellonaStruttura Dipartimentale Di Emostasi E Trombosi, AOU Di Cagliari, Cagliari, Italy.
Piera SiveraSCDU Ematologia, Ospedale Mauriziano Torino, Torin, Italy.
Attilia Maria PizziniUOC Medicina A- Ospedale Maggiore, Bologna, Italy.
Giuseppe VercilloUO Patologia Clinica-IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Daniele Pastori *Department of Medical and Cardiovascular Sciences, University of Rome "Sapienza", 00161, Rome, Italy.
Pasquale Pignatelli *Department of Medical and Cardiovascular Sciences, University of Rome "Sapienza", 00161, Rome, Italy. Pasquale.pignatelli@uniroma1.it.ORCID http://orcid.org/0000-0002-2265-7455
START-A. P. S. Investigators^

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with thrombotic antiphospholipid syndrome (APS) or subjects with persistent presence of antiphospholipid antibodies (aPLA), defined "carriers", may develop thrombocytopenia. However, the prevalence and clinical characteristics associated with thrombocytopenia remain poorly understood. We aimed to describe the prevalence and the clinical characteristics associated with thrombocytopenia in APS patients and aPLA carriers included in the Survey on AnTicoAgulated Patients-RegisTry on antiphospholipid antibodies (START-APS), a multicentre prospective registry. Thrombocytopenia was defined as a platelet count < 150 × 10

Indexed as

Antiphospholipid SyndromeThrombocytopeniaAdultAgedAntibodies, AntiphospholipidFemaleHumansLogistic ModelsMaleMiddle AgedPrevalenceProspective StudiesRegistriesAntibodies, AntiphospholipidAntiphospholipid antibodiesAntiphospholipid syndromeCarriersThrombocytopenia

Identifiers

PMID42303888

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.