Evidence map›Paper›PMID 42303879›Full record

SynthesisCardiovascular and interventional radiology2026

Outcome and Safety of Genicular Artery Embolization for Knee Osteoarthritis: A Systematic Review and Meta-Analysis.

Arian Taheri Amin, Isaac Eli Martínez Safar, Ricardo Baquero Trujillo, Juan Guillermo Trujillo Buritica, Osman Ahmed, Kai Jannusch, Peter Minko

Abstract readSystematic ReviewMeta-AnalysisReview
In one paragraph

Synthesis in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Young Procedure Under a Mature Standard: The Evolving Evidence for GAE.Cardiovascular and interventional radiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arian Taheri Amin *Department of Diagnostic and Interventional Radiology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany. arian.taheri-amin@charite.de.ORCID http://orcid.org/0000-0002-3532-7383
Isaac Eli Martínez Safar *School of Medicine, Faculty of Health Sciences, Universidad Libre Seccional Barranquilla, Barranquilla, Colombia.
Ricardo Baquero TrujilloDepartment of Radiology and Diagnostic Imaging, Clínica Reina Sofía, Bogotá, Colombia.
Juan Guillermo Trujillo BuriticaDepartment of Radiology and Diagnostic Imaging, Clínica Reina Sofía, Bogotá, Colombia.
Osman AhmedJoint and Vascular Institute, Libertyville, IL, USA.
Kai JannuschDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Hospital Duesseldorf, Campus Virchow-Klinikum (CVK), Augustenburger Platz 1, D-40225, Duesseldorf, Germany.
Peter MinkoDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Hospital Duesseldorf, Campus Virchow-Klinikum (CVK), Augustenburger Platz 1, D-40225, Duesseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review and meta-analysis evaluated pain and functional outcomes, safety, and differences between embolic agents in genicular artery embolization (GAE) for knee osteoarthritis. Forty-five studies including 2205 patients were analyzed. Across predominantly uncontrolled studies, clinically relevant improvements were observed, with pooled Visual Analogue Scale reductions of - 37.5 points at 1 month and - 37.1 at 12 months. Western Ontario and McMaster Universities Osteoarthritis Index improved by - 28.9 at 1 month, and Knee Injury and Osteoarthritis Outcome Score-Pain by + 23.6 at 6 months. Mean changes exceeded clinically important thresholds. No significant subgroup interaction between permanent and temporary embolic agents was observed. The most frequent adverse events were transient skin discoloration (11%) and hematoma (3%). Overall, the certainty of evidence ranged from very low to low.Graphical Abstract.

Indexed as

Embolization, TherapeuticOsteoarthritis, KneeHumansPain MeasurementTreatment OutcomeGenicular artery embolizationKnee osteoarthritisMeta-analysisMinimally invasive treatmentPainSystematic review

Identifiers

PMID42303879
PMCPMC13597475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.