Evidence map›Paper›PMID 42303869›Full record

ReviewDiscover nano2026

Research progress and prospects of nanomaterials in imaging of central nervous system diseases.

Houfan Li, Lihua Deng, Zongqian Wu, Chen Liu

Abstract readReview
In one paragraph

Review in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Houfan Li *Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), 30 Gao Tan Yan St, Chongqing, 400038, China.
Lihua Deng *Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), 30 Gao Tan Yan St, Chongqing, 400038, China.
Zongqian WuDepartment of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), 30 Gao Tan Yan St, Chongqing, 400038, China. wuzongqian@tmmu.edu.cn.
Chen LiuDepartment of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), 30 Gao Tan Yan St, Chongqing, 400038, China. liuchen@tmmu.edu.cn.

Funding

Natural Science Foundation of China 82071910Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission CSTB2024NSCQ-MSX3439
6 · The paper itself

Abstract

Nanomaterials have garnered significant attention in recent years for their application in the imaging of central nervous system diseases (CNSDs). To comprehensively understand the research progress and trends in this field, this paper conducted a bibliometric analysis of relevant literature over the past fourteen years, systematically reviewing the research hotspots and development trends in the application of nanomaterials for CNSDs imaging. Using CiteSpace for visual data analysis, relationship networks among countries, institutions, journals, research categories, authors, and keywords were presented through specified mapping. The findings reveal that China is the country with the highest number of publications, the Chinese Academy of Sciences is the institution with the most published articles, and "Biomaterials" is the most frequently cited journal. Keywords such as fluorescence imaging, release, proteins, and targeted delivery represent current research hotspots, indicating a shift in focus toward precision imaging and intelligent delivery. Cluster analysis reveals that current research has progressed from single-performance optimization to the development of intelligent responsive nano-systems-integrating targeted delivery, environmentally responsive release, and multimodal imaging. However, nanomaterials still face multiple challenges and limitations spanning from basic research to clinical translation, and their application in CNSDs remains experimental. Therefore, further interdisciplinary research across materials science, chemistry, biology, and medicine is necessary to break down disciplinary barriers and promote clinical translation, ultimately enabling revolutionary breakthroughs in nano-theranostic technologies for central nervous system diseases.

Indexed as

Central nervous system diseasesCiteSpaceImagingNanomaterials

Identifiers

PMID42303869
PMCPMC13272736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.