ArticleAmerican journal of preventive medicine2026
Neighborhood Deprivation and Contrasting Patterns of Prenatal Alcohol, Cannabis, and Nicotine Use.
Article in American journal of preventive medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
introductionNeighborhood context is an important social determinant of health behaviors, including substance use, but less is known about whether neighborhood deprivation is similarly or differentially related to prenatal use of alcohol, cannabis, and nicotine.
methodsUsing electronic health record data from Kaiser Permanente Northern California, this retrospective observational study examined geographic variation in prenatal alcohol, cannabis, and nicotine use and evaluated whether neighborhood deprivation was associated with use of these substances during pregnancy. The sample included 173,578 pregnancies (November 2020-December 2024) among members with prenatal screening for substance use during early pregnancy as part of standard care. Neighborhood deprivation index (NDI) from geocoded census data was categorized into quartiles. Choropleth maps visualized tract-level prevalence of prenatal substance use, and modified Poisson regression models estimated associations between NDI quartiles and prenatal substance use using individual-level data. Data were analyzed July 2025-Feburary 2026.
resultsPrevalence of prenatal alcohol, cannabis, and nicotine was 9.6%, 8.9% and 2.0%, respectively. Compared with pregnancies in the least deprived neighborhoods, those in the most deprived neighborhoods had a lower prevalence of prenatal alcohol use (aPR [95% CI] = 0.87 [0.84, 0.92]), but higher prevalence of prenatal cannabis (aPR [95% CI] =1.80 [1.70, 1.90]) and nicotine use (aPR [95% CI] = 1.96 [1.74, 2.20]).
conclusionsNeighborhood deprivation showed opposing associations across substances, with lower alcohol use but substantially higher cannabis and nicotine use in more deprived neighborhoods. Findings underscore the importance of considering neighborhood context and type of substance when developing preventive interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.