Evidence map›Paper›PMID 42302463›Full record

ArticleBrazilian journal of otorhinolaryngology

Cortical auditory response and language development in children with microcephaly by Zika virus.

Ana Cláudia Figueiredo Frizzo, Kelly Cristina Lira de Andrade, Isabela Tiezi Rombola, Klinger Vagner Teixeira da Costa, Eduardo Federighi Baisi Chagas, Pedro de Lemos Menezes

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Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ana Cláudia Figueiredo FrizzoUniversidade Estadual de São Paulo (UNESP), Faculdade de Filosofia e Ciências, Department of Speech Therapy and Postgraduate Program in Speech Therapy, Marilia, SP, Brazil. Electronic address: ana.frizzo@unesp.br.
Kelly Cristina Lira de AndradeUniversidade Federal de Alagoas, Biotechnology in Health ‒ RENORBIO, Maceió, AL, Brazil; Universidade Estadual de Ciências da Saúde de Alagoas (UNCISAL), Maceió, AL, Brazil.
Isabela Tiezi RombolaUniversidade Estadual de São Paulo (UNESP), Faculdade de Filosofia e Ciências, Marília, SP, Brazil.
Klinger Vagner Teixeira da CostaUniversidade Federal de Alagoas, Biotechnology in Health ‒ RENORBIO, Maceió, AL, Brazil; CESMAC School of Medicine, Maceió, AL, Brazil.
Eduardo Federighi Baisi ChagasUniversidade Estadual de São Paulo (UNESP), Rio Claro, SP, Brazil; Universidade de Marília (UNIMAR), Marília, SP, Brazil; Universidade de Marília (UNIMAR), Interdisciplinary Master's Program in Structural and Functional Interactions in the Rehabilitation, Marília, SP, Brazil.
Pedro de Lemos MenezesUniversidade Estadual de Ciências da Saúde de Alagoas (UNCISAL), Maceió, AL, Brazil; CESMAC Health Research Graduate Program, Maceió, AL, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study proposes to assess the auditory and linguistic development of children with microcephaly due to maternal Zika virus infection and to understand the influence of this condition on auditory cortical responses and language development.

methodsThe cross-sectional descriptive study was carried out in the northeast of Brazil. Twenty children (mean age 27-months), of both sexes, with and without microcephaly due to Zika virus participated in the study. For auditory cortical responses, 40 natural /ba/ and /da/ monoaural speech sounds were presented at 70 dB HLeP. The Early Language Milestone Scale assessed the development status of auditory and visual functions related to language. For statistical analysis, covariance measures (ANCOVA) and Pearson's correlation tests were used. The Bonferroni post-hoc test was applied to significant F-values (p < 0.05). The Smart tools EP software was used to improve the investigation of the electrical response and to bring accurate and automated analyzes.

resultsLonger values were observed in the latency of the N1-P2 components and a higher N1 amplitude of the cortical responses in children with microcephaly. Changes in the scale showed a significant impairment in language development in these children. Smart showed abnormalities in the neurotransmission of acoustic characteristics related to frequency information in the auditory pathway in children with microcephaly.

conclusionThe measurements of the study showed a pattern of atypical development of the auditory and linguistic system in children with microcephaly due to the Zika virus. LEVEL OF EVIDENCE: 3*.

Indexed as

Auditory CortexEvoked Potentials, AuditoryLanguage DevelopmentLanguage Development DisordersMicrocephalyZika Virus InfectionBrazilChild, PreschoolCross-Sectional StudiesFemaleHumansMaleAuditory developmentAuditory evoked potentialsMicrocephalyZika virus

Identifiers

PMID42302463
PMCPMC13285280

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.