ArticleJournal of animal physiology and animal nutrition2026
Prenatal Exposure to Different Nitrogen Supplementation Strategies in Beef Cows Enhances Foetal Growth and Induces Transcriptional Adaptations in Offspring Skeletal Muscle.
Article in Journal of animal physiology and animal nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
This study aimed to assess the effects of different nitrogen supplementation strategies during mid-gestation on postnatal performance, skeletal muscle gene expression and morphology and nutritional and metabolic parameters of beef offspring during both the cow-calf and backgrounding phases. Thirty Zebu cows (532 ± 11 kg of body weight [BW]) were used. The following treatments were randomly assigned to cows from 127 ± 17 to 227 ± 17 days of gestation: (1) Control (CON; n = 10): basal diet (corn silage + sugarcane bagasse) and a mineral supplement with urea (60 g/100 kg BW); (2) Rumen-degradable protein (RDP; n = 10): basal diet plus a commercial protein supplement (250 g/100 kg BW) and ground corn (44 g/100 kg BW); and (3) Rumen-undegradable protein (RUP; n = 10): basal diet plus protected soybean meal (3.5 g/kg BW) and a mineral supplement with urea (60 g/100 kg BW). After supplementation, cows were managed as a single group on pasture. Offspring were evaluated during the cow-calf phase, and in a 60-day feedlot backgrounding phase. At the end of the supplementation period (227 days of gestation), cows in the RUP treatment had greater BW compared to those in the CON and RDP treatments (p = 0.01). Near parturition (282 days of gestation), no differences in BW were observed among treatments (p = 0.28). Birth weight was greater in the RUP group compared to the CON and RDP groups (p = 0.04), with no differences between the CON and RDP. No effects of treatment were observed on offspring weaning weight, average daily gain, ultrasound carcass traits, nutrient intake, apparent total tract digestibility, ingestive behaviour or muscle fibre number and histomorphometry (p > 0.05). At 346 ± 31 days of age, RUP offspring exhibited increased expression of skeletal muscle genes, including ACACA, FASN, PPARG, CPT2, IGF1R and COL3A1 compared to the CON group (p ≤ 0.05). Additionally, RUP offspring showed greater expression of ACACA, FABP4, PPARA, SCD1, COL3A1 and IGFR1 compared to RDP offspring (p ≤ 0.04). In conclusion, maternal supplementation with rumen-protected protein during mid-gestation enhances foetal growth and induces beneficial transcriptional adaptations in skeletal muscle compared to non-protein or RDP supplementation strategies, without affecting postnatal growth performance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.