Evidence map›Paper›PMID 42301936›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2026

Inhibition of Ice Recrystallization by Regulating the Surface Free Energy of Nanoparticles.

Xin Li, Jiayu Weng, Yiyang Guo, Min Li, Yubin Ma, Chen Li, Yang Liu, Xuehu Ma, Changying Xue, Yi Zuo and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xin LiState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China.
Jiayu WengCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Yiyang GuoState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China.
Min LiState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China.
Yubin MaState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China.
Chen LiCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Yang LiuState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China.
Xuehu MaSchool of Chemical Engineering, Dalian University of Technology, Dalian, China.ORCID https://orcid.org/0000-0002-9496-3734
Changying XueSchool of Bioengineering, Dalian University of Technology, Dalian, China.
Yi ZuoDepartment of Mechanical Engineering, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Zhanfeng CuiInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Yi HeCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Nan XuCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Bingbing SunState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China.ORCID https://orcid.org/0000-0002-5444-5078

Funding

Fundamental Research Funds for the Central Universities DUT22LAB601Fundamental Research Funds for the Central Universities DUT22QU225National Key Research and Development Program of China 2022YFC2304305National Natural Science Foundation of China 22178299National Natural Science Foundation of China 51933009National Natural Science Foundation of China U22A20455
6 · The paper itself

Abstract

Nanoparticles (NPs) have emerged as ice-control materials to prevent damage caused by low-temperature-induced ice crystals. However, the mechanism of ice recrystallization inhibition (IRI) of NPs is poorly understood. A thorough understanding of the relationships between the physicochemical properties of nanomaterials and their IRI ability remains to be established. In this study, we prepared a comprehensive library of NPs, including Stöber silica, poly(lactic-co-glycolic acid) (PLGA), and Au NPs with tunable physicochemical properties, and examined their IRI functionalities. The results revealed that the surface free energy (SFE) of NPs was closely related to their IRI ability, which was further supported by molecular dynamics (MD) simulations. Our findings highlight the critical role of nanomaterials' SFE in mediating their IRI activity, advancing the fundamental understanding of the mechanism underlying NP-controlled ice recrystallization. This study provides a novel design strategy for developing nanoparticles as ice-control materials.

Indexed as

hydrophilicityice recrystallization inhibitionnanomaterialsurface free energy

Identifiers

PMID42301936
PMCPMC13472256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.