Evidence map›Paper›PMID 42301502›Full record

ArticleNeuroradiology2026

Quantitative assessment of perfusion-weighted magnetic resonance imaging for the differential diagnosis of various intraocular lesions.

Iris Mulder, Khanh Vu, Teresa Ferreira, Lisa Klaassen, Jan-Willem Beenakker

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Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Iris MulderDepartment of Ophthalmology, Leiden University Medical Center, Leiden, Netherlands. i.e.mulder@lumc.nl.
Khanh VuDepartment of Ophthalmology, Leiden University Medical Center, Leiden, Netherlands.
Teresa FerreiraDepartment of Radiology, Leiden University Medical Center, Leiden, Netherlands.
Lisa KlaassenDepartment of Ophthalmology, Leiden University Medical Center, Leiden, Netherlands.
Jan-Willem BeenakkerDepartment of Ophthalmology, Leiden University Medical Center, Leiden, Netherlands.

Funding

KWF Kankerbestrijding 2019: 12184Nederlandse Organisatie voor Wetenschappelijk Onderzoek 19704
6 · The paper itself

Abstract

purposeTo conduct an exploratory analysis of quantitative and semi-quantitative perfusion-weighted MRI (PWI) parameters across various intraocular lesions and assess their relationship with fluorescein angiography (FAG) features.

methodsThirty-eight patients with twelve different diagnoses who underwent 3T dynamic contrast-enhanced MRI (DCE-MRI) of the eye were included, with diagnosis confirmed either by histopathology or clinical course of the disease. Tofts pharmacokinetic modelling was used to calculate K

resultsMedian values of quantitative and semi-quantitative parameters varied across lesion types. Haemangiomas showed the highest K

conclusionThis study provided quantitative and semi-quantitative PWI parameters for various intraocular lesions. Semi-quantitative PWI parameters may provide comparable information on lesion vascularity when stratified by T1 signal intensity.

Indexed as

Eye NeoplasmsAdultAgedAged, 80 and overContrast MediaDiagnosis, DifferentialDynamic Contrast Enhanced Magnetic Resonance ImagingFemaleFluorescein AngiographyHumansMaleMelanomaMiddle AgedPerfusion Magnetic Resonance ImagingRetrospective StudiesContrast MediaFluorescein angiographyMagnetic resonance imagingOcular oncologyPerfusionTofts modelUveal melanoma

Identifiers

PMID42301502
PMCPMC13578002

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.