Evidence map›Paper›PMID 42301483›Full record

ArticleParasitology research2026

Molecular detection and zoonotic genotyping of Enterocytozoon bieneusi in Siberian tigers (Panthera tigris altaica), Northeast China.

Hang Tian, Zhiying Cui, Zhiyou Lv, Mengqiu Liu, Yang Liu, Yilin Zhao, Weiyan Yin, Mengru Zhao, Hongyan Yu, Mengchao Zhou and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasitology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hang Tian *Laboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Zhiying Cui *Laboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Zhiyou LvLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Mengqiu LiuLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Yang LiuLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Yilin ZhaoLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Weiyan YinLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Mengru ZhaoLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Hongyan YuLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Mengchao ZhouLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Yaxian LuLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China.
Dapeng LiSiberian Tiger Park, Harbin, 150028, People's Republic of China.
Ming GongSiberian Tiger Park, Harbin, 150028, People's Republic of China.
Haitao XuSiberian Tiger Park, Harbin, 150028, People's Republic of China. 59231835@qq.com.
Zhijun HouLaboratory of Vector-Borne Diseases and Pathogens Ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, People's Republic of China. houzhijundb@163.com.ORCID https://orcid.org/0000-0002-8704-1651

Funding

National Key Research and Development Program of China 2023YFF1305402
6 · The paper itself

Abstract

Enterocytozoon bieneusi is an important zoonotic pathogen. This study examined its prevalence and genotypes in Siberian tigers in Northeast China. Fecal samples from 97 captive and 5 wild tigers were analyzed by nested PCR targeting the ITS region. Prevalence in captive tigers was 40.2% (39/97), with no significant site differences. Three genotypes were identified: D (89.7%), Peru8 (7.7%), and Type IV (2.6%), all within zoonotic Group 1. E. bieneusi was detected for the first time in a wild Siberian tiger (genotype D). The predominance of genotype D-common in poultry-suggests dietary transmission through contaminated chicken meat. These results indicate high prevalence of zoonotic genotypes in tigers, underscoring cross-species transmission risks and the need for strengthened biosecurity and surveillance.

Indexed as

EnterocytozoonMicrosporidiosisTigersZoonosesAnimalsChinaDNA, FungalDNA, Ribosomal SpacerFecesGenotypePhylogenyPolymerase Chain ReactionPrevalenceSequence Analysis, DNADNA, FungalDNA, Ribosomal SpacerChinaEnterocytozoon bieneusiGenotypeITSPanthera tigris altaica

Identifiers

PMID42301483
PMCPMC13506582

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.