Evidence map›Paper›PMID 42301262›Full record

ArticleAnalytical chemistry2026

To the homeRNAmax: Developing an Improved Blood Self-Collection and Stabilization Platform for Remote Transcriptomic Studies.

Madeleine Eakman, Filip Stefanovic, Jean Berthier, Ingrid H Robertson, Liam A Knudsen, Celiane Cardoso Carvalho, Kyra Chen, Jane Atkeson, Stephanie Eichman, Serena H Nguyen and 12 more

Abstract read
In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Madeleine EakmanDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Filip StefanovicDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-1448-9578
Jean BerthierDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Ingrid H RobertsonDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Liam A KnudsenDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0009-0004-9349-1845
Celiane Cardoso CarvalhoDivision of Rheumatology, New York University School of Medicine, New York, New York 10016, United States.
Kyra ChenDivision of Rheumatology, New York University School of Medicine, New York, New York 10016, United States.
Jane AtkesonDivision of Rheumatology, New York University School of Medicine, New York, New York 10016, United States.
Stephanie EichmanDivision of Rheumatology, New York University School of Medicine, New York, New York 10016, United States.
Serena H NguyenDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Cosette A CraigDepartment of Mechanical Engineering, University of Washington, Seattle, Washington 98195, United States.
Kelsey M LeongDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.ORCID 0009-0004-4258-9009
Damon Wing Hey ChanDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Karen N AdamsDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Ayokunle O OlanrewajuDepartment of Mechanical Engineering, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0003-4776-1774
Sanitta ThongpangDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Tristan M NicholsonDepartment of Urology, School of Medicine, University of Washington, Seattle, Washington 98195, United States.
Rebecca H HabermanDivision of Rheumatology, New York University School of Medicine, New York, New York 10016, United States.
Jose U ScherDivision of Rheumatology, New York University School of Medicine, New York, New York 10016, United States.
Erwin BerthierDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Ashleigh B ThebergeDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-3394-1435
Amanda J HaackDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Theberge Admin Supp Undergraduate Summer Research ExperiencesR35GM128648 · NIGMS · UNIVERSITY OF WASHINGTON · PI Ashleigh Brooks Theberge · 2018 to 2026
$4.7M
University of Washington Pediatric and Reproductive Environmental Health Scholars (UW PREHS)K12ES033584 · NIEHS · UNIVERSITY OF WASHINGTON · PI CATHERINE J KARR, Sheela Sathyanarayana · 2022 to 2026
$2.4M
Precision Monitoring of Treatment Response in Early Psoriatic Arthritis: Integrating at-Home RNA Microsampling into Ongoing, Remote, Smart Phone-Based, Digital Data CapturingR01AR084274 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Jose U. Scher, Ashleigh Brooks Theberge · 2024 to 2026
$1.2M
NCATS NIH HHS UL1 TR002319NIAMS NIH HHS R01 AR084274NIEHS NIH HHS K12 ES033584NIGMS NIH HHS R35 GM128648
6 · The paper itself

Abstract

Shifting human subjects research from research sites to participants' homes removes barriers to participation. Previously, we developed homeRNA, a kit for stabilization of RNA in self-collected blood using a custom-engineered tube containing RNA stabilizer fluid. The stabilized RNA is extracted and used for downstream gene expression analysis. Here, we introduce homeRNAmax, which improves our original design by interfacing with a commercially available blood collection tube (BD Microtainer), allowing homeRNAmax to be used with any blood collection method that uses this tube and doubling the possible sample volume that can be collected and stabilized compared to the original homeRNA. Through a pilot study (

Indexed as

Blood Specimen CollectionGene Expression ProfilingRNATranscriptomeHumansPilot ProjectsRNA StabilityRNA

Identifiers

PMID42301262
PMCPMC13481057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.