Evidence map›Paper›PMID 42300766›Full record

ArticlemBio2026

Sorafenib, a clinical kinase inhibitor, attenuates

Joel Abraham, Aswathy C Sagilkumar, Himani Dhyani, Charmi M Panchal, Shaheena Aziz, M K Priyadatha, Aan Ruth, Keerthana Bhaskaran, Sivakumar Krishnankutty Chandrika, S Shaima and 6 more

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Joel AbrahamHost-Pathogen Laboratory, Pathogen Biology Division, BRIC-Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB), Thiruvananthapuram, India.ORCID 0000-0001-7938-9247
Aswathy C SagilkumarHost-Pathogen Laboratory, Pathogen Biology Division, BRIC-Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB), Thiruvananthapuram, India.ORCID 0009-0004-7182-2455
Himani DhyaniHost-Pathogen Laboratory, Pathogen Biology Division, BRIC-Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB), Thiruvananthapuram, India.
Charmi M PanchalHost-Pathogen Laboratory, Pathogen Biology Division, BRIC-Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB), Thiruvananthapuram, India.
Shaheena AzizHost-Pathogen Laboratory, Pathogen Biology Division, BRIC-Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB), Thiruvananthapuram, India.
M K PriyadathaHost-Pathogen Laboratory, Pathogen Biology Division, BRIC-Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB), Thiruvananthapuram, India.
Aan RuthSchool of Biology, Indian Institute of Science Education and Research, Thiruvananthapuram, India.
Keerthana BhaskaranSchool of Biology, Indian Institute of Science Education and Research, Thiruvananthapuram, India.
Sivakumar Krishnankutty ChandrikaBioinformatics Facility, BRIC-RGCB, Thiruvananthapuram, India.
S ShaimaTransdisciplinary Biology Program, BRIC-Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India.
Rosemol VargheseDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Ayyanraj NeeraviDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Balaji VeeraragavanDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Nagarjun NarayanaswamyTransdisciplinary Biology Program, BRIC-Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India.
Sandhya GanesanSchool of Biology, Indian Institute of Science Education and Research, Thiruvananthapuram, India.
Karthik SubramanianHost-Pathogen Laboratory, Pathogen Biology Division, BRIC-Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB), Thiruvananthapuram, India.ORCID 0000-0002-4381-5037

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IMPORTANCE:

Indexed as

Anti-Bacterial AgentsPneumococcal InfectionsProtein Kinase InhibitorsSorafenibStreptococcus pneumoniaeAnimalsDisease Models, AnimalDisease ProgressionFemaleHumansMiceMicrobial Sensitivity TestsProtein Serine-Threonine KinasesAnti-Bacterial AgentsProtein Kinase InhibitorsProtein Serine-Threonine KinasesSorafenibantimicrobial resistancedrug repurposingserine threonine kinasesorafenibStkPStreptococcus pneumoniae

Identifiers

PMID42300766
PMCPMC13343887

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.