Evidence map›Paper›PMID 42299934›Full record

ReviewLab on a chip2026

Integrated microfluidic biosensors: shaping the future of quantitative life sciences and on-chip molecular diagnostics.

Ty Naquin, Chloe Naquin, Qian Wu, Ying Chen, Aidan Canning, Kaichun Yang, Yuna Li, Shuaiguo Zhao, Yun Ling, Zhiteng Ma and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lab on a chip, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ty NaquinThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.ORCID 0009-0003-4897-2677
Chloe NaquinThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.
Qian WuThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.ORCID 0000-0002-4252-1109
Ying ChenThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.ORCID 0009-0000-4812-7658
Aidan CanningThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.ORCID 0000-0002-8001-6496
Kaichun YangThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.
Yuna LiThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.
Shuaiguo ZhaoThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.
Yun LingThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.
Zhiteng MaThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.
Ke JinThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.
Ye HeThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.
Shujie YangThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.ORCID 0000-0003-2626-3397
Luke P LeeDivision of Engineering in Medicine, Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. lplee@bwh.harvard.edu.
Tony Jun HuangThomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. shujie.yang@seas.upenn.edu.ORCID 0000-0003-1205-3313

Funding

Automated High-purity Exosome isolation-based AD diagnostics system (AHEADx)R01AG084098 · NIA · DUKE UNIVERSITY · PI Tony Jun Huang · 2023 to 2026
$3.1M
Acoustofluidic Separation of Placental Nanovesicle Subpopulations in Obstetrical DiseasesR01HD103727 · NICHD · STANFORD UNIVERSITY · PI HUANG, TONY JUN, SADOVSKY, YOEL · 2021 to 2025
$2.6M
An acoustofluidic device for diagnosing preclinical Alzheimer's diseaseR44AG063643 · NIA · ASCENT BIO-NANO TECHNOLOGIES, INC. · PI WANG, LIN · 2021 to 2022
$2.5M
Development of the AcoustoDrop platform: an acoustofluidic-based, automated, liquid-handling system for manipulating and dispensing dropletsin a rewritable, biocompatible, and high-throughput mannerR44GM154515 · NIGMS · ASCENT BIO-NANO TECHNOLOGIES, INC. · PI WANG, LIN · 2024 to 2025
$2.2M
Development of an acoustic-based smart Petri dish for contact-free, precise, versatile bioparticle manipulationR44GM154514 · NIGMS · ASCENT BIO-NANO TECHNOLOGIES, INC. · PI WANG, LIN · 2024 to 2025
$2.0M
Development of a digital acoustofluidic system for automating liquid handling in biomedical researchR01GM141055 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2021 to 2024
$1.9M
Harmonic Acoustics for Neighboring cell Dynamic studies(HANDs)R01GM145960 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI LEE, LUKE P. · 2022 to 2025
$1.8M
Development of a multifunctional, acoustofluidic 3D bioprinter with single-cell resolutionR01GM144417 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Zhenhua Tian · 2022 to 2026
$1.8M
An Acoustofluidic Device for Biocompatible Platelet SeparationR44HL140800 · NHLBI · ASCENT BIO-NANO TECHNOLOGIES, INC. · PI WANG, LIN · 2021 to 2022
$1.5M
Three-Dimensional (3D) Acoustofluidic Scanning Nanoscope with Super Resolution and Large Field of ViewR01GM143439 · NIGMS · UNIVERSITY OF DAYTON · PI AGHA, IMAD, HUANG, TONY JUN · 2021 to 2024
$1.5M
National Science Foundation CMMI-2104295NHLBI NIH HHS R44 HL140800NIA NIH HHS R01 AG084098NIA NIH HHS R44 AG063643NICHD NIH HHS R01 HD103727NIGMS NIH HHS R01 GM141055NIGMS NIH HHS R01 GM143439NIGMS NIH HHS R01 GM144417NIGMS NIH HHS R01 GM145960NIGMS NIH HHS R44 GM154514NIGMS NIH HHS R44 GM154515
6 · The paper itself

Abstract

Integrated microfluidic biosensors have rapidly evolved into powerful platforms to meet the increasing demand for ultrasensitive and high-throughput quantitative analysis. By seamlessly combining sample handling through microfluidics with real-time detection

Indexed as

Biosensing TechniquesLab-On-A-Chip DevicesMicrofluidic Analytical TechniquesAnimalsHumans

Identifiers

PMID42299934
PMCPMC13220791

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.