Evidence map›Paper›PMID 42299869›Full record

ArticleeLife2026

Host and antibiotic jointly select for greater virulence in

Michelle Su, Kim L Hoang, McKenna Penley, Michelle H Davis, Jennifer D Gresham, Levi T Morran, Timothy D Read

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The dynamic interplay betweenFrontiers in cellular and infection microbiology · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Michelle Su *Emory University School of Medicine, Division of Infectious Diseases, Atlanta, United States.
Kim L Hoang *Emory University School of Medicine, Division of Infectious Diseases, Atlanta, United States.ORCID https://orcid.org/0000-0001-5269-1630
McKenna PenleyDepartment of Biology, Emory University, Atlanta, United States.
Michelle H DavisEmory University School of Medicine, Division of Infectious Diseases, Atlanta, United States.
Jennifer D GreshamDepartment of Biology, Emory University, Atlanta, United States.
Levi T MorranDepartment of Biology, Emory University, Atlanta, United States.ORCID https://orcid.org/0000-0002-6422-0374
Timothy D ReadEmory University School of Medicine, Division of Infectious Diseases, Atlanta, United States.ORCID https://orcid.org/0000-0001-8966-9680

Funding

Georgia Department of Public Health CK22-2204National Science Foundation 1750553NIH HHS AI106699NIH HHS AI139188NIH HHS AI158452
6 · The paper itself

Abstract

Widespread antibiotic usage has resulted in the rapid evolution of drug-resistant bacterial pathogens. Resolving how pathogens respond to antibiotics under different contexts is critical for understanding disease emergence. It remains unclear how interactions between hosts and antibiotics impact pathogen evolution. Here, we evolved

Indexed as

Anti-Bacterial AgentsHost-Pathogen InteractionsSelection, GeneticStaphylococcus aureusAnimalsCaenorhabditis elegansDrug Resistance, BacterialHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMutationStaphylococcal InfectionsVirulenceAnti-Bacterial Agentsantibiotic resistanceC. elegansevolutionary biologyexperimental evolutioninfectious diseasemicrobiologyS. aureus

Identifiers

PMID42299869
PMCPMC13271738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.