ArticleBioMed research international2026
Assessment of Sealing Ability and Degradation Resistance of a Hydrogel-Based Root Canal Filling Material Using a Bacterial Leakage Model and SEM Analysis.
Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Assessment of Sealing Ability and Degradation Resistance of a Hydrogel-Based Root Canal Filling Material Using a Bacterial Leakage Model and SEM Analysis.BioMed research international · 2026Article
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7 authors.
Funding
Abstract
backgroundThis study evaluated the sealing ability and degradation resistance of a novel hydrogel-based, low-viscosity, light-curable obturation material compared with gutta-percha combined with an epoxy resin-based sealer using a bacterial leakage model and scanning electron microscopy (SEM) analysis.
methodsThirty-seven extracted single-rooted bovine incisors were allocated into four groups: gutta-percha + epoxy resin sealer (n = 12), hydrogel-based material (n = 10), positive control with empty canals (n = 11), and negative control (n = 4). Bacterial leakage was assessed using a two-chamber model inoculated with Enterococcus faecalis. Survival times were analyzed using nonparametric tests. For degradation analysis, 30 hydrogel specimens (n = 6 per medium) were incubated in phosphate-buffered saline (PBS), brain heart infusion (BHI) broth, E. faecalis suspension, sterile-filtered saliva, or pH 10 carbonate buffer. SEM-based Feret diameter measurements were obtained after 1, 8, and 30 days and analyzed using Kruskal-Wallis and Holm-adjusted Mann-Whitney U tests.
resultsThe first leakage occurred after 11 days in the gutta-percha group and after 58 days in the hydrogel group. Forty percent failure was observed after 22 days for gutta-percha and after 121 days for the hydrogel material (p < 0.001). Mean Feret diameter increased most markedly under alkaline conditions (Δ = +0.100 μm from Day 1 to Day 30; p < 0.001), whereas changes in PBS, BHI, E. faecalis, and saliva remained below 0.05 μm over 30 days.
conclusionsThe hydrogel-based obturation material demonstrated significantly prolonged resistance to bacterial penetration and maintained structural stability under biologically relevant incubation conditions. Further long-term and in vivo studies are required to confirm clinical performance.
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