ReviewTrauma surgery & acute care open2026
Whole truth: resuscitating trauma patients with whole blood.
Review in Trauma surgery & acute care open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- TCCACS and MDR 2026 introduction.Trauma surgery & acute care open · 2026Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hemorrhage remains the leading cause of death from potentially survivable injuries in both military and civilian trauma. Whole blood (WB) has repeatedly proven to be the most physiologically coherent resuscitation strategy for life-threatening hemorrhage, yet modern transfusion systems have historically prioritized inventory efficiency and component fractionation over biologic fidelity. This syllabus synthesizes contemporary military and civilian evidence for WB resuscitation, with emphasis on fresh WB (FWB) obtained through walking blood banks (WBBs) and low-titer group O WB (LTOWB), the predominant WB product currently used in civilian trauma. The historical 'back to the future' arc of transfusion practice, pathophysiology of trauma-induced blood failure, and the most current transfusion outcome data are summarized. The future of both military and civilian trauma resuscitation should adopt a layered approach to transfusion-this supports the best outcomes for trauma patients and also supports the trauma system. Precision resuscitation frameworks that assess clinical outcomes for type and timing of blood transfusion have the potential to support advanced resuscitation practices. Although the academic literature lacks publications on comparisons of LTOWB and FWB, the military is actively performing analysis to determine if there are outcome benefits for FWB and revisiting the concept for
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.