ArticleGland surgery2026
Systemic corticosteroid bridging followed by ultrasound-guided microwave ablation for recurrent male plasma cell mastitis: a case report.
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Plasma cell mastitis (PCM) is a chronic inflammatory breast disorder that primarily affects women. It is exceptionally rare in men and poses a diagnostic challenge due to its high recurrence rate and features that can mimic malignancy. Currently, there is no standardized treatment protocol for refractory PCM, particularly for recurrent cases in male patients. The aim of this case report is to present a unique instance of recurrent male PCM that was successfully managed with a stepwise approach: initial corticosteroid therapy followed by ultrasound-guided microwave ablation (MWA). Accordingly, this minimally invasive and tissue-preserving approach could be considered a treatment option alongside conventional surgical resection for managing such challenging recurrences. Case Description: A 30-year-old man presented with an ipsilateral recurrence of a retroareolar mass, accompanied by erythema and swelling, 18 months after initial surgical excision. Imaging and core needle biopsy confirmed recurrent PCM with suppurative inflammation. To avoid the trauma of repeat open surgery, the patient was treated with a step-up regimen: systemic corticosteroids (prednisone) were first administered to reduce the acute inflammatory burden, followed by ultrasound-guided MWA for definitive local control. At the 18-month follow-up, there was no clinical or sonographic evidence of recurrence, and the patient reported high cosmetic satisfaction and significantly improved quality of life compared with his initial surgery. Conclusions: The main take-away lesson from this case is that a step-up approach-corticosteroid bridging followed by MWA-offers a promising, minimally invasive alternative to repeat surgery for recurrent male PCM. This strategy provides a significant clinical impact by balancing effective disease control with superior cosmetic outcomes. Further prospective studies are warranted to confirm its long-term implications.
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