ArticleGland surgery2026
Cryoablation-guided breast-conserving surgery: a single-center, retrospective study based on a propensity score-matched cohort.
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Background: Currently, surgical resection remains the first choice for treating early breast cancer. Cryoablation, a minimally invasive ablative technique, can inactivate the target tumor Methods: This study retrospectively analyzed the clinical characteristics and treatment data of patients who underwent BCS at our center between December 2024 and December 2025. After propensity score matching (PSM), 111 patients were paired: 37 in the cryoablation group and 74 in the surgery group. The clinical data of both groups were compared to evaluate the feasibility of cryoablation-guided BCS for early-stage breast cancer, its impact on the outcomes of BCS and sentinel lymph node biopsy (SLNB). Results: Ultrasound-guided cryoablation was successfully performed under local anesthesia in all 37 patients, with a complete ablation rate of 94.59% [35/37; 95% confidence interval (CI): 82.3-98.5%]. Compared to the surgery group, the cryoablation group had a lower rate of positive or close margin for BCS (5.41% Conclusions: This retrospective study demonstrated that cryoablation-guided BCS was feasible and safe. Compared to standard BCS, cryoablation-guided BCS was associated with a higher accuracy in resection, a lower positive or close margin rate, shorter surgical duration and post-operative LOS. Additionally, cryoablation did not negatively impact the success rate of subsequent SLNB.
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