ArticleCureus2026
False-Positive Prostate-Specific Membrane Antigen (PSMA) PET Uptake in the Vocal Cords Mimicking Metastatic Disease in Prostate Cancer: A Case Report Highlighting Diagnostic Pitfalls.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) is increasingly used in prostate cancer imaging because of its high sensitivity for detecting metastatic disease, even at low prostate-specific antigen (PSA) levels. However, false-positive uptake may occur in benign or inflammatory conditions, creating important diagnostic pitfalls. We report the case of a patient with oligometastatic low-volume prostate adenocarcinoma who presented with biochemical progression and a PSA level of 10.85 ng/mL. Histopathology confirmed a high-grade adenocarcinoma (International Society of Urological Pathology {ISUP} grade 5, Gleason score 9 {5+4}). PSMA PET/CT demonstrated intense uptake within the prostate gland and an additional focal uptake in the vocal cords, initially suspicious for atypical metastatic disease. Subsequent otorhinolaryngological evaluation with fiberoptic laryngoscopy was normal, supporting the diagnosis of false-positive PSMA uptake. This case highlights the limitations of PSMA PET specificity and emphasizes the importance of correlating imaging findings with clinical, anatomical, and endoscopic evaluations to avoid misdiagnosis, overstaging, and inappropriate therapeutic decisions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.