Evidence map›Paper›PMID 42299185›Full record

ArticleCureus2026

Anabolic Steroid-Induced Cholestatic Jaundice in a Young Adult: An Emerging Clinical Challenge Underscoring the Importance of a Thorough Drug History.

Min Kyaw Han, Winluck Shayo, Zaw Thant Lwin, Moe Thazin Aung, Cynthia Cheng

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Min Kyaw HanAcute Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, GBR.
Winluck ShayoAcute Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, GBR.
Zaw Thant LwinAcute Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, GBR.
Moe Thazin AungNeurology, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, GBR.
Cynthia ChengAcute Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anabolic-androgenic steroids (AASs) are synthetic derivatives of testosterone with both androgenic and anabolic properties, and their non-medical use has been increasingly reported, particularly among young adults. Although licensed for conditions such as hypogonadism and cachexia, AASs are frequently misused for rapid muscle growth and performance enhancement. Such unregulated use carries a significant risk of drug-induced liver injury, most commonly presenting with a cholestatic pattern. Here, we describe a case of a previously healthy young bodybuilder who developed severe cholestatic jaundice after seven weeks of unsupervised anabolic steroid use. This case highlights the importance of thorough drug history taking, including over-the-counter supplements and performance-enhancing agents, in any young adult presenting with unexplained jaundice. Early recognition and prompt withdrawal of the offending agent resulted in marked clinical improvement and steady normalisation of liver function tests.

Indexed as

anabolic-androgenic steroidsbodybuilding supplementscholestasisdrug-induced liver injurymethandrostenoloneperformance-enhancing drugs

Identifiers

PMID42299185
PMCPMC13264516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.