Evidence map›Paper›PMID 42299145›Full record

ArticleOrthopedic reviews2026

Perioperative Visual Loss After Spine Surgery: A Case-Based Review of Posterior Ischemic Optic Neuropathy.

Anvinh Nguyen, Jamal Hasoon, Tommy Li, Christopher L Robinson, Vu Nguyen

Abstract read
In one paragraph

Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anvinh NguyenDepartment of Anesthesiology Baylor College of Medicine.
Jamal HasoonDepartment of Anesthesiology, Critical Care, and Pain Medicine The University of Texas Health Science Center at Houston.
Tommy LiDepartment of Anesthesiology Baylor College of Medicine.
Christopher L RobinsonDepartment of Anesthesiology and Critical Care, Division of Pain Medicine The Johns Hopkins University School of Medicine.
Vu NguyenDepartment of Anesthesiology Baylor College of Medicine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perioperative visual loss (POVL) is an uncommon but life-altering complication that has been reported most often after prolonged spine procedures performed in the prone position. Among the recognized causes, posterior ischemic optic neuropathy (PION) accounts for the majority of cases in this setting and is believed to result from impaired perfusion of the retrobulbar optic nerve. Clinical and registry data consistently associate PION with intraoperative anemia, sustained or relative hypotension, substantial blood loss, large-volume fluid administration with hemodilution, and preexisting vascular disease that limits autoregulatory reserve. Advanced age and systemic atherosclerotic burden further increase susceptibility by reducing the optic nerve's tolerance to ischemic stress. This case-based educational review describes an elderly patient with significant systemic diseases, including vasculopathy, who developed acute, painless visual loss after lumbar spinal surgery. Using this clinical scenario, we examine the interplay between patient-specific risk factors and intraoperative physiology, review the underlying vascular anatomy and pathophysiology of PION, and outline an approach to early recognition and differential diagnosis of postoperative visual deficits. Management principles are discussed with an emphasis on hemodynamic optimization, prompt specialist consultation, and realistic counseling regarding prognosis. The goal of this structured discussion is to provide anesthesiology trainees and perioperative clinicians with a practical framework to recognize high-risk situations, implement preventive strategies, and respond appropriately should this rare but catastrophic complication occur.

Indexed as

anemiaAnesthesiahypotensionneurosurgeryorthopedic surgeryperioperative visual lossposterior ischemic optic neuropathyprone positioningspine surgery

Identifiers

PMID42299145
PMCPMC13265056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.